Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia

S. Zurrida, L. Contu, A. Bono, C. Bartoli, V. Galimberti, L. Demelia, N. Rossi, F. Pitzus

Research output: Contribution to journalArticle

Abstract

Ten patients suffering from the Classical Kaposi's Sarcoma (CKS) were studied to show the possible existence of a subgroup of this illness in the Mediterranean, as hypothesized by other authors. For this reason, we analyzed the peripheral hematological and medullar picture together with the immunological, immunogenetic and cytogenetic profile of ten patients in Sardinia. The hematological picture did not show any characteristics peculiar of CKS either in the peripheral blood or in the bone marrow; however, the involvement of the T-lymphocyte system and the association of this kind of neoplasia with the HLA-DR5 antigen was confirmed. Finally, different kinds of non-specific cytogenetic alterations were found in far greater numbers than expected. No alterations affording a particular picture of Mediterranean KS were shown to exist even though diserythro and dismyelopoietic hematological pictures were present.

Original languageEnglish
Pages (from-to)147-152
Number of pages6
JournalEuropean Journal of Internal Medicine
Volume3
Issue number2
Publication statusPublished - 1992

Fingerprint

Kaposi's Sarcoma
Cytogenetics
Italy
HLA-DR5 Antigen
Immunogenetics
Bone Marrow
T-Lymphocytes
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)
  • Internal Medicine

Cite this

Zurrida, S., Contu, L., Bono, A., Bartoli, C., Galimberti, V., Demelia, L., ... Pitzus, F. (1992). Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia. European Journal of Internal Medicine, 3(2), 147-152.

Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia. / Zurrida, S.; Contu, L.; Bono, A.; Bartoli, C.; Galimberti, V.; Demelia, L.; Rossi, N.; Pitzus, F.

In: European Journal of Internal Medicine, Vol. 3, No. 2, 1992, p. 147-152.

Research output: Contribution to journalArticle

Zurrida, S, Contu, L, Bono, A, Bartoli, C, Galimberti, V, Demelia, L, Rossi, N & Pitzus, F 1992, 'Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia', European Journal of Internal Medicine, vol. 3, no. 2, pp. 147-152.
Zurrida, S. ; Contu, L. ; Bono, A. ; Bartoli, C. ; Galimberti, V. ; Demelia, L. ; Rossi, N. ; Pitzus, F. / Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia. In: European Journal of Internal Medicine. 1992 ; Vol. 3, No. 2. pp. 147-152.
@article{437abb5c09314e2ea036cba514a47628,
title = "Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia",
abstract = "Ten patients suffering from the Classical Kaposi's Sarcoma (CKS) were studied to show the possible existence of a subgroup of this illness in the Mediterranean, as hypothesized by other authors. For this reason, we analyzed the peripheral hematological and medullar picture together with the immunological, immunogenetic and cytogenetic profile of ten patients in Sardinia. The hematological picture did not show any characteristics peculiar of CKS either in the peripheral blood or in the bone marrow; however, the involvement of the T-lymphocyte system and the association of this kind of neoplasia with the HLA-DR5 antigen was confirmed. Finally, different kinds of non-specific cytogenetic alterations were found in far greater numbers than expected. No alterations affording a particular picture of Mediterranean KS were shown to exist even though diserythro and dismyelopoietic hematological pictures were present.",
author = "S. Zurrida and L. Contu and A. Bono and C. Bartoli and V. Galimberti and L. Demelia and N. Rossi and F. Pitzus",
year = "1992",
language = "English",
volume = "3",
pages = "147--152",
journal = "European Journal of Internal Medicine",
issn = "0953-6205",
publisher = "Elsevier B.V.",
number = "2",

}

TY - JOUR

T1 - Hematological findings in 10 cases of classic Kaposi's Sarcoma in Sardinia

AU - Zurrida, S.

AU - Contu, L.

AU - Bono, A.

AU - Bartoli, C.

AU - Galimberti, V.

AU - Demelia, L.

AU - Rossi, N.

AU - Pitzus, F.

PY - 1992

Y1 - 1992

N2 - Ten patients suffering from the Classical Kaposi's Sarcoma (CKS) were studied to show the possible existence of a subgroup of this illness in the Mediterranean, as hypothesized by other authors. For this reason, we analyzed the peripheral hematological and medullar picture together with the immunological, immunogenetic and cytogenetic profile of ten patients in Sardinia. The hematological picture did not show any characteristics peculiar of CKS either in the peripheral blood or in the bone marrow; however, the involvement of the T-lymphocyte system and the association of this kind of neoplasia with the HLA-DR5 antigen was confirmed. Finally, different kinds of non-specific cytogenetic alterations were found in far greater numbers than expected. No alterations affording a particular picture of Mediterranean KS were shown to exist even though diserythro and dismyelopoietic hematological pictures were present.

AB - Ten patients suffering from the Classical Kaposi's Sarcoma (CKS) were studied to show the possible existence of a subgroup of this illness in the Mediterranean, as hypothesized by other authors. For this reason, we analyzed the peripheral hematological and medullar picture together with the immunological, immunogenetic and cytogenetic profile of ten patients in Sardinia. The hematological picture did not show any characteristics peculiar of CKS either in the peripheral blood or in the bone marrow; however, the involvement of the T-lymphocyte system and the association of this kind of neoplasia with the HLA-DR5 antigen was confirmed. Finally, different kinds of non-specific cytogenetic alterations were found in far greater numbers than expected. No alterations affording a particular picture of Mediterranean KS were shown to exist even though diserythro and dismyelopoietic hematological pictures were present.

UR - http://www.scopus.com/inward/record.url?scp=0026574748&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026574748&partnerID=8YFLogxK

M3 - Article

VL - 3

SP - 147

EP - 152

JO - European Journal of Internal Medicine

JF - European Journal of Internal Medicine

SN - 0953-6205

IS - 2

ER -