Hematopoietic stem cell transplantation in Europe 2014: More than 40 000 transplants annually

Jakob Passweg, H. Baldomero, P. Bader, Chiara Bonini, S. Cesaro, P. Dreger, R. F. Duarte, Carlo Dufour, Jürgen H E Kuball, Dominique Farge-Bancel, Andrew Gennery, Nicolaus Kröger, F. Lanza, Arnon Nagler, Anna Sureda, Mohamad Mohty

Research output: Contribution to journalArticle

Abstract

A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.

Original languageEnglish
Pages (from-to)786-792
Number of pages7
JournalBone Marrow Transplantation
Volume51
Issue number6
DOIs
Publication statusPublished - Jun 1 2016

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Hematopoietic Stem Cell Transplantation
Transplants
Fetal Blood
Tissue Donors
Neoplasms
Unrelated Donors
Aplastic Anemia
Amyloidosis
Growth
Plasma Cells
Leukemia
Stem Cells

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Passweg, J., Baldomero, H., Bader, P., Bonini, C., Cesaro, S., Dreger, P., ... Mohty, M. (2016). Hematopoietic stem cell transplantation in Europe 2014: More than 40 000 transplants annually. Bone Marrow Transplantation, 51(6), 786-792. https://doi.org/10.1038/bmt.2016.20

Hematopoietic stem cell transplantation in Europe 2014 : More than 40 000 transplants annually. / Passweg, Jakob; Baldomero, H.; Bader, P.; Bonini, Chiara; Cesaro, S.; Dreger, P.; Duarte, R. F.; Dufour, Carlo; Kuball, Jürgen H E; Farge-Bancel, Dominique; Gennery, Andrew; Kröger, Nicolaus; Lanza, F.; Nagler, Arnon; Sureda, Anna; Mohty, Mohamad.

In: Bone Marrow Transplantation, Vol. 51, No. 6, 01.06.2016, p. 786-792.

Research output: Contribution to journalArticle

Passweg, J, Baldomero, H, Bader, P, Bonini, C, Cesaro, S, Dreger, P, Duarte, RF, Dufour, C, Kuball, JHE, Farge-Bancel, D, Gennery, A, Kröger, N, Lanza, F, Nagler, A, Sureda, A & Mohty, M 2016, 'Hematopoietic stem cell transplantation in Europe 2014: More than 40 000 transplants annually', Bone Marrow Transplantation, vol. 51, no. 6, pp. 786-792. https://doi.org/10.1038/bmt.2016.20
Passweg, Jakob ; Baldomero, H. ; Bader, P. ; Bonini, Chiara ; Cesaro, S. ; Dreger, P. ; Duarte, R. F. ; Dufour, Carlo ; Kuball, Jürgen H E ; Farge-Bancel, Dominique ; Gennery, Andrew ; Kröger, Nicolaus ; Lanza, F. ; Nagler, Arnon ; Sureda, Anna ; Mohty, Mohamad. / Hematopoietic stem cell transplantation in Europe 2014 : More than 40 000 transplants annually. In: Bone Marrow Transplantation. 2016 ; Vol. 51, No. 6. pp. 786-792.
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