Hemispheric asymmetry of pattern reversal visual evoked potentials in healthy subjects

Pattern reversal visual evoked potentials were recorded from temporal leads of both hemispheres in 3 right-handed and 3 left-handed subjects. The stimuli subtended 6° of visual field (full field condition), or 1° of visual field (foveal condition), or were restricted to the peripheral portion of the visual field (annular condition). Check sizes varied from 16 to 2.8 min of arc. The stimuli were phase-reversed at 1 or 8 Hz. Remarkable hemispheric asymmetries were found, depending on the portion of the visual field and temporal frequency. In right-handed subjects the amplitude of visual evoked potentials recorded over the left hemisphere was larger for stimuli phase-reversed at 8 Hz in full-field and annular conditions, whereas the amplitude of visual evoked potentials recorded over the right hemisphere was larger for stimuli phase-reversed at 1 Hz in the foveal condition. Different patterns of hemispheric asymmetries were observed in left-handed subjects.