Hemocompatibility of carotid artery stents: Alterations of the electrical parameters of erythrocyte cell membrane-A word of caution

Antonio Basoli, Cesare Cametti, Vittorio Faraglia, Tommaso Gili, Luigi Rizzo, Maurizio Taurino

Research output: Contribution to journalArticle

Abstract

The hemocompatibility of standard surgical treatment of carotid artery disease through the insertion of metallic stents is investigated by means of radio wave dielectric spectroscopy technique that allows the measurements of the electrical parameters of the red blood cell membrane. Our measurements suggest that both the membrane permittivity and the membrane conductivity, which characterize the overall electrical behavior of the cell membrane, undergo an appreciable alteration of their standard values as a consequence of the stent insertion. These alterations persist over long period of time, up to 4 weeks. Even if these effects could not cause any evident damage at physiological or clinical level to the patient, the presence of a host response to the stent implant suggests that a full hemocompatibility has not yet reached, and a word of caution is necessary.

Original languageEnglish
Pages (from-to)190-197
Number of pages8
JournalVascular and Endovascular Surgery
Volume44
Issue number3
DOIs
Publication statusPublished - Apr 2010

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Keywords

  • Blood cell membrane
  • Carotid artery disease
  • Metallic stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

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