Beneficio emodinamico della stimolazione sequenziale atrio-ventricolare.

Translated title of the contribution: Hemodynamic benefits of sequential atrioventricular pacing

S. Ghio, G. Marinoni, P. Broglia, E. Eleuteri, F. Barba, G. Bargiggia, C. Bosatra, V. Pantusa, R. Perotti, C. Montemartini

Research output: Contribution to journalArticlepeer-review


The purpose of this study was to evaluate the hemodynamic benefits of atrioventricular (A-V) sequential pacing. 30 pts implanted with DDD pacemakers underwent M-mode, B-mode and Doppler echocardiography. In each patient, left ventricular (LV) stroke volume was assessed by measuring the time-velocity integral of mitral inflow in the following modes and rates: VOO at 70 ppm or at the minimum stimulation rate and at 120 ppm; DOO at the same rates with different A-V delay (100, 150, 200, 250 and, whenever possible, 300 msec). The increase in stroke volume obtained with dual chamber pacing at the optimal A-V delay was 45 +/- 25% at 75 ppm and 29 +/- 14% at 120 ppm (p less than 0.05 75 vs 120 ppm). This increase was significantly higher in pts with than in pts without LV hypertrophy (respectively: 51.9 +/- 20.4 vs 36.9 +/- 20.8% at 75 ppm, p less than 0.05 and 33 +/- 13.4 vs 25.4 +/- 14.5% at 120 ppm, p = 0.08). Concerning the A-V delay, we noted that at 75 ppm stroke volume was significantly higher in DOO than in VOO with any A-V delay ranging +/- 100 msec from the optimal one; at 120 ppm the hemodynamic benefit of DOO pacing was observed only when the programmed A-V delay was the optimal one or very near to it. In conclusion, atrio-ventricular sequential pacing allows a significant increase in LV stroke volume over single chamber ventricular pacing both at 75 and 120 ppm. Programming the optimal A-V delay is absolutely necessary to obtain this hemodynamic benefit at the higher stimulation rate.

Translated title of the contributionHemodynamic benefits of sequential atrioventricular pacing
Original languageItalian
Pages (from-to)957-964
Number of pages8
JournalGiornale Italiano di Cardiologia
Issue number9
Publication statusPublished - Sep 1991

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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