Hemodynamic patterns of chronic cerebrospinal venous insufficiency in multiple sclerosis. Correlation with symptoms at onset and clinical course

I. Bartolomei, Fabrizio Salvi, R. Galeotti, E. Salviato, M. Alcanterini, E. Menegatti, M. Mascalchi, P. Zamboni

Research output: Contribution to journalArticlepeer-review

Abstract

Aim. Chronic cerebrospinal venous insufficiency (CCSVI) is associated with multiple sclerosis (MS). CCSVI is detected by transcranial and extracranial color-Doppler high-resolution examination (TCCS-ECD) and venography that permit to identify five types of venous malformations and four major (A-D) hemodynamic patterns of anomalous extracranial-extravertebral venous outflow. We investigated possible correlation between such hemodynamic patterns and both the symptoms at onset and clinical course in patients with MS and CCSVI. Methods. TCCS-ECD, selective venography and clinical records of 65 patients affected by definite MS and CCSVI were reviewed. Results. The four hemodynamic patterns of CCSVI were unevenly (P

Original languageEnglish
Pages (from-to)183-188
Number of pages6
JournalInternational Angiology
Volume29
Issue number2
Publication statusPublished - Apr 2010

Keywords

  • Cerebrospinal fluid
  • Multiple sclerosis
  • Venous insufficiency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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