An experimental model of hypertrophic pyloric stenosis was made by suture of the pyloric wall and gastrostomy in 10 rabbits under general anesthesia. Blood sampling indicated severe alkalosis and hypochloremia 3 h 30 min after surgery. To correct the derangement, we tested an ion exchange resin (Dowex SAR), coated with a methacrylic hydrogel. A cartridge containing 18 g of this resin was inserted in an extracorporeal circuit. This chloride charged resin achieved uptake of HCO3 - ions, and elution of Cl- ions. The electrolytic balance was fully restored after 10 min of treatment.
|Number of pages||4|
|Journal||International Journal of Artificial Organs|
|Publication status||Published - 1992|
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