Abstract
Objective: To investigate the hemoreologic, hemostatic and metabolic effects of a monophasic low-dose oral contraceptive. Methods: Twenty healthy young women desiring hormonal contraception were studied before, during and after a 2 year course of a monophasic oral contraceptive containing gestodene 75 μg and ethinylestradiol 30 μg. Twenty-nine matched healthy young women were chosen as the control group. Results: No differences in any of the variables evaluated (body mass index, blood pressure, erythrocyte deformability, concentrations of triglycerides, total HDL, LDL and VLDL cholesterol, non-esterified fatty acids, serum lipoproteins VLDL, LDL, HDL and apolipoproteins A, A1 and B, fibrinogen, fibronectin, von Willebrand factor antigen, α2-macroglobulin, antithrombin III, prolactin) were demonstrated between the women taking the monophasic pill and the control group. Conclusion: Oral contraception with the monophasic gestodene and ethinylestradiol combination may be a safe long-term hormonal contraceptive method for young women and prevent the development of cardiovascular complications.
| Original language | English |
|---|---|
| Pages (from-to) | 85-91 |
| Number of pages | 7 |
| Journal | Italian Journal of Gynaecology and Obstetrics |
| Volume | 5 |
| Issue number | 3 |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Hemorheological, hemostatic and metabolic long-term (24 months) study of young women taking a monophasic pill containing gestodene and ethinylestradiol. / Solerte, S. B.; Fioravanti, M.; Spinillo, A.; Capuzzo, E.; Iasci, A.; Mastrolilli, M.; Berard, P.; Reboli, P.; Ferrari, E.; Guaschino, S.
In: Italian Journal of Gynaecology and Obstetrics, Vol. 5, No. 3, 1993, p. 85-91.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Hemorheological, hemostatic and metabolic long-term (24 months) study of young women taking a monophasic pill containing gestodene and ethinylestradiol
AU - Solerte, S. B.
AU - Fioravanti, M.
AU - Spinillo, A.
AU - Capuzzo, E.
AU - Iasci, A.
AU - Mastrolilli, M.
AU - Berard, P.
AU - Reboli, P.
AU - Ferrari, E.
AU - Guaschino, S.
PY - 1993
Y1 - 1993
N2 - Objective: To investigate the hemoreologic, hemostatic and metabolic effects of a monophasic low-dose oral contraceptive. Methods: Twenty healthy young women desiring hormonal contraception were studied before, during and after a 2 year course of a monophasic oral contraceptive containing gestodene 75 μg and ethinylestradiol 30 μg. Twenty-nine matched healthy young women were chosen as the control group. Results: No differences in any of the variables evaluated (body mass index, blood pressure, erythrocyte deformability, concentrations of triglycerides, total HDL, LDL and VLDL cholesterol, non-esterified fatty acids, serum lipoproteins VLDL, LDL, HDL and apolipoproteins A, A1 and B, fibrinogen, fibronectin, von Willebrand factor antigen, α2-macroglobulin, antithrombin III, prolactin) were demonstrated between the women taking the monophasic pill and the control group. Conclusion: Oral contraception with the monophasic gestodene and ethinylestradiol combination may be a safe long-term hormonal contraceptive method for young women and prevent the development of cardiovascular complications.
AB - Objective: To investigate the hemoreologic, hemostatic and metabolic effects of a monophasic low-dose oral contraceptive. Methods: Twenty healthy young women desiring hormonal contraception were studied before, during and after a 2 year course of a monophasic oral contraceptive containing gestodene 75 μg and ethinylestradiol 30 μg. Twenty-nine matched healthy young women were chosen as the control group. Results: No differences in any of the variables evaluated (body mass index, blood pressure, erythrocyte deformability, concentrations of triglycerides, total HDL, LDL and VLDL cholesterol, non-esterified fatty acids, serum lipoproteins VLDL, LDL, HDL and apolipoproteins A, A1 and B, fibrinogen, fibronectin, von Willebrand factor antigen, α2-macroglobulin, antithrombin III, prolactin) were demonstrated between the women taking the monophasic pill and the control group. Conclusion: Oral contraception with the monophasic gestodene and ethinylestradiol combination may be a safe long-term hormonal contraceptive method for young women and prevent the development of cardiovascular complications.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027521650&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0027521650
VL - 5
SP - 85
EP - 91
JO - Italian Journal of Gynaecology and Obstetrics
JF - Italian Journal of Gynaecology and Obstetrics
SN - 1121-8339
IS - 3
ER -