Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

Monica Arena, Enzo Masci, Leonardo Henry Eusebi, Giuseppe Iabichino, Benedetto Mangiavillano, Paolo Viaggi, Elisabetta Morandi, Lorella Fanti, Antonino Granata, Mario Traina, Pier Alberto Testoni, Enrico Opocher, Carmelo Luigiano

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings. Aims: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer. Methods: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study. Results: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30. days and 50% at six months. Conclusion: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

Original languageEnglish
JournalDigestive and Liver Disease
DOIs
Publication statusE-pub ahead of print - Sep 7 2016

Keywords

  • Hemospray
  • New endoscopic hemostatic treatment
  • Upper gastrointestinal cancer
  • Upper gastrointestinal neoplastic bleeding

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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