Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

Monica Arena, Enzo Masci, Leonardo Henry Eusebi, Giuseppe Iabichino, Benedetto Mangiavillano, Paolo Viaggi, Elisabetta Morandi, Lorella Fanti, Antonino Granata, Mario Traina, Pier Alberto Testoni, Enrico Opocher, Carmelo Luigiano

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.

AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.

METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.

RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.

CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

Original languageEnglish
Pages (from-to)514-517
Number of pages4
JournalDigestive and Liver Disease
Volume49
Issue number5
DOIs
Publication statusPublished - May 2017

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Hemorrhage
Neoplasms
Therapeutics
Injections
Hemostatics
Hemostasis
Powders
Endoscopy
hemospray
Hot Temperature
Databases
Safety

Keywords

  • Journal Article

Cite this

Arena, M., Masci, E., Eusebi, L. H., Iabichino, G., Mangiavillano, B., Viaggi, P., ... Luigiano, C. (2017). Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. Digestive and Liver Disease, 49(5), 514-517. https://doi.org/10.1016/j.dld.2016.12.012

Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. / Arena, Monica; Masci, Enzo; Eusebi, Leonardo Henry; Iabichino, Giuseppe; Mangiavillano, Benedetto; Viaggi, Paolo; Morandi, Elisabetta; Fanti, Lorella; Granata, Antonino; Traina, Mario; Testoni, Pier Alberto; Opocher, Enrico; Luigiano, Carmelo.

In: Digestive and Liver Disease, Vol. 49, No. 5, 05.2017, p. 514-517.

Research output: Contribution to journalArticle

Arena, M, Masci, E, Eusebi, LH, Iabichino, G, Mangiavillano, B, Viaggi, P, Morandi, E, Fanti, L, Granata, A, Traina, M, Testoni, PA, Opocher, E & Luigiano, C 2017, 'Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours', Digestive and Liver Disease, vol. 49, no. 5, pp. 514-517. https://doi.org/10.1016/j.dld.2016.12.012
Arena, Monica ; Masci, Enzo ; Eusebi, Leonardo Henry ; Iabichino, Giuseppe ; Mangiavillano, Benedetto ; Viaggi, Paolo ; Morandi, Elisabetta ; Fanti, Lorella ; Granata, Antonino ; Traina, Mario ; Testoni, Pier Alberto ; Opocher, Enrico ; Luigiano, Carmelo. / Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. In: Digestive and Liver Disease. 2017 ; Vol. 49, No. 5. pp. 514-517.
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AU - Arena, Monica

AU - Masci, Enzo

AU - Eusebi, Leonardo Henry

AU - Iabichino, Giuseppe

AU - Mangiavillano, Benedetto

AU - Viaggi, Paolo

AU - Morandi, Elisabetta

AU - Fanti, Lorella

AU - Granata, Antonino

AU - Traina, Mario

AU - Testoni, Pier Alberto

AU - Opocher, Enrico

AU - Luigiano, Carmelo

N1 - Copyright © 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

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N2 - BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

AB - BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

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