Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

Monica Arena; Enzo Masci; Leonardo Henry Eusebi; Giuseppe Iabichino; Benedetto Mangiavillano; Paolo Viaggi; Elisabetta Morandi; Lorella Fanti; Antonino Granata; Mario Traina; Pier Alberto Testoni; Enrico Opocher; Carmelo Luigiano

doi:10.1016/j.dld.2016.12.012

Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

Monica Arena, Enzo Masci, Leonardo Henry Eusebi, Giuseppe Iabichino, Benedetto Mangiavillano, Paolo Viaggi, Elisabetta Morandi, Lorella Fanti, Antonino Granata, Mario Traina, Pier Alberto Testoni, Enrico Opocher, Carmelo Luigiano

Research output: Contribution to journal › Article

Abstract

BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.

AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.

METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.

RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.

CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

Original language	English
Pages (from-to)	514-517
Number of pages	4
Journal	Digestive and Liver Disease
Volume	49
Issue number	5
DOIs	https://doi.org/10.1016/j.dld.2016.12.012
Publication status	Published - May 2017

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Arena, M., Masci, E., Eusebi, L. H., Iabichino, G., Mangiavillano, B., Viaggi, P., Morandi, E., Fanti, L., Granata, A., Traina, M., Testoni, P. A., Opocher, E., & Luigiano, C. (2017). Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. Digestive and Liver Disease, 49(5), 514-517. https://doi.org/10.1016/j.dld.2016.12.012

Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. / Arena, Monica; Masci, Enzo; Eusebi, Leonardo Henry; Iabichino, Giuseppe; Mangiavillano, Benedetto; Viaggi, Paolo; Morandi, Elisabetta; Fanti, Lorella; Granata, Antonino ; Traina, Mario ; Testoni, Pier Alberto; Opocher, Enrico; Luigiano, Carmelo.

In: Digestive and Liver Disease, Vol. 49, No. 5, 05.2017, p. 514-517.

Research output: Contribution to journal › Article

Arena, Monica ; Masci, Enzo ; Eusebi, Leonardo Henry ; Iabichino, Giuseppe ; Mangiavillano, Benedetto ; Viaggi, Paolo ; Morandi, Elisabetta ; Fanti, Lorella ; Granata, Antonino ; Traina, Mario ; Testoni, Pier Alberto ; Opocher, Enrico ; Luigiano, Carmelo. / Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. In: Digestive and Liver Disease. 2017 ; Vol. 49, No. 5. pp. 514-517.

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abstract = "BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.",

keywords = "Journal Article",

author = "Monica Arena and Enzo Masci and Eusebi, {Leonardo Henry} and Giuseppe Iabichino and Benedetto Mangiavillano and Paolo Viaggi and Elisabetta Morandi and Lorella Fanti and Antonino Granata and Mario Traina and Testoni, {Pier Alberto} and Enrico Opocher and Carmelo Luigiano",

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doi = "10.1016/j.dld.2016.12.012",

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T1 - Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

AU - Arena, Monica

AU - Masci, Enzo

AU - Eusebi, Leonardo Henry

AU - Iabichino, Giuseppe

AU - Mangiavillano, Benedetto

AU - Viaggi, Paolo

AU - Morandi, Elisabetta

AU - Fanti, Lorella

AU - Granata, Antonino

AU - Traina, Mario

AU - Testoni, Pier Alberto

AU - Opocher, Enrico

AU - Luigiano, Carmelo

PY - 2017/5

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N2 - BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

AB - BACKGROUND: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.AIMS: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.METHODS: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.RESULTS: Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30days and 50% at six months.CONCLUSION: Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings.

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DO - 10.1016/j.dld.2016.12.012

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JO - Digestive and Liver Disease

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SN - 1590-8658

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10.1016/j.dld.2016.12.012