Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

M Arena, E Masci, LH Eusebi, G Iabichino, B Mangiavillano, P Viaggi, E Morandi, Lorella Fanti, A Granata, M Traina, PA Testoni, E Opocher, C Luigiano

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Abstract

Background Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings. Aims To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer. Methods The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study. Results Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30 days and 50% at six months. Conclusion Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings. © 2016 Editrice Gastroenterologica Italiana S.r.l.
Original languageEnglish
Pages (from-to)514-517
Number of pages4
JournalDigestive and Liver Disease
Volume49
Issue number5
DOIs
Publication statusPublished - 2017

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Hemorrhage
Neoplasms
Therapeutics
Injections
Hemostatics
Hemostasis
Powders
Endoscopy
hemospray
Hot Temperature
Databases
Safety

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Arena, M., Masci, E., Eusebi, LH., Iabichino, G., Mangiavillano, B., Viaggi, P., ... Luigiano, C. (2017). Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. Digestive and Liver Disease, 49(5), 514-517. https://doi.org/10.1016/j.dld.2016.12.012

Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. / Arena, M; Masci, E; Eusebi, LH; Iabichino, G; Mangiavillano, B; Viaggi, P; Morandi, E; Fanti, Lorella; Granata, A; Traina, M; Testoni, PA; Opocher, E; Luigiano, C.

In: Digestive and Liver Disease, Vol. 49, No. 5, 2017, p. 514-517.

Research output: Contribution to journalArticle

Arena, M, Masci, E, Eusebi, LH, Iabichino, G, Mangiavillano, B, Viaggi, P, Morandi, E, Fanti, L, Granata, A, Traina, M, Testoni, PA, Opocher, E & Luigiano, C 2017, 'Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours', Digestive and Liver Disease, vol. 49, no. 5, pp. 514-517. https://doi.org/10.1016/j.dld.2016.12.012
Arena, M ; Masci, E ; Eusebi, LH ; Iabichino, G ; Mangiavillano, B ; Viaggi, P ; Morandi, E ; Fanti, Lorella ; Granata, A ; Traina, M ; Testoni, PA ; Opocher, E ; Luigiano, C. / Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours. In: Digestive and Liver Disease. 2017 ; Vol. 49, No. 5. pp. 514-517.
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abstract = "Background Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings. Aims To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer. Methods The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study. Results Immediate haemostasis was achieved in 93{\%} of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80{\%} of patients had a good clinical outcome at 30 days and 50{\%} at six months. Conclusion Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings. {\circledC} 2016 Editrice Gastroenterologica Italiana S.r.l.",
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T1 - Hemospray for treatment of acute bleeding due to upper gastrointestinal tumours

AU - Arena, M

AU - Masci, E

AU - Eusebi, LH

AU - Iabichino, G

AU - Mangiavillano, B

AU - Viaggi, P

AU - Morandi, E

AU - Fanti, Lorella

AU - Granata, A

AU - Traina, M

AU - Testoni, PA

AU - Opocher, E

AU - Luigiano, C

PY - 2017

Y1 - 2017

N2 - Background Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings. Aims To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer. Methods The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study. Results Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30 days and 50% at six months. Conclusion Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings. © 2016 Editrice Gastroenterologica Italiana S.r.l.

AB - Background Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings. Aims To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer. Methods The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study. Results Immediate haemostasis was achieved in 93% of cases. Among the successful cases, 3 re-bled, one case treated with Hemospray and injection had a good outcome, while 2 cases died both re-treated with Hemospray, injection and thermal therapy. No complications related to Hemospray occurred. Finally, 80% of patients had a good clinical outcome at 30 days and 50% at six months. Conclusion Hemospray may be considered an effective and safe method for the endoscopic management of acute neoplastic upper gastrointestinal bleedings. © 2016 Editrice Gastroenterologica Italiana S.r.l.

U2 - 10.1016/j.dld.2016.12.012

DO - 10.1016/j.dld.2016.12.012

M3 - Article

VL - 49

SP - 514

EP - 517

JO - Digestive and Liver Disease

JF - Digestive and Liver Disease

SN - 1590-8658

IS - 5

ER -