Abstract
Chronic liver disease is characterized by a global hemostatic defect that includes platelet-vessel wall interaction (primary hemostasis), fibrinolysis and coagulation causing abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with bleeding. Recent evidence from the literature disputes the above paradigm and open new directions for laboratory and clinical research in this field. Copyright by Medycyna Praktyczna, 2008.
Original language | English |
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Pages (from-to) | 445-448 |
Number of pages | 4 |
Journal | Polskie Archiwum Medycyny Wewnetrznej |
Volume | 118 |
Issue number | 7-8 |
Publication status | Published - 2008 |
Keywords
- Chronic liver disease
- Coagulation
- Coagulopathy
- Liver transplantation
- Prognosis
ASJC Scopus subject areas
- Internal Medicine