Abstract
Chronic liver disease is characterized by a global hemostatic defect that includes platelet-vessel wall interaction (primary hemostasis), fibrinolysis and coagulation causing abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with bleeding. Recent evidence from the literature disputes the above paradigm and open new directions for laboratory and clinical research in this field. Copyright by Medycyna Praktyczna, 2008.
| Original language | English |
|---|---|
| Pages (from-to) | 445-448 |
| Number of pages | 4 |
| Journal | Polskie Archiwum Medycyny Wewnetrznej |
| Volume | 118 |
| Issue number | 7-8 |
| Publication status | Published - 2008 |
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Keywords
- Chronic liver disease
- Coagulation
- Coagulopathy
- Liver transplantation
- Prognosis
ASJC Scopus subject areas
- Internal Medicine
Cite this
Hemostasis abnormalities in liver cirrhosis : Myth or reality? / Tripodi, Armando.
In: Polskie Archiwum Medycyny Wewnetrznej, Vol. 118, No. 7-8, 2008, p. 445-448.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hemostasis abnormalities in liver cirrhosis
T2 - Myth or reality?
AU - Tripodi, Armando
PY - 2008
Y1 - 2008
N2 - Chronic liver disease is characterized by a global hemostatic defect that includes platelet-vessel wall interaction (primary hemostasis), fibrinolysis and coagulation causing abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with bleeding. Recent evidence from the literature disputes the above paradigm and open new directions for laboratory and clinical research in this field. Copyright by Medycyna Praktyczna, 2008.
AB - Chronic liver disease is characterized by a global hemostatic defect that includes platelet-vessel wall interaction (primary hemostasis), fibrinolysis and coagulation causing abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with bleeding. Recent evidence from the literature disputes the above paradigm and open new directions for laboratory and clinical research in this field. Copyright by Medycyna Praktyczna, 2008.
KW - Chronic liver disease
KW - Coagulation
KW - Coagulopathy
KW - Liver transplantation
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=49249083985&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=49249083985&partnerID=8YFLogxK
M3 - Article
C2 - 18714742
AN - SCOPUS:49249083985
VL - 118
SP - 445
EP - 448
JO - Polskie Archiwum Medycyny Wewnetrznej
JF - Polskie Archiwum Medycyny Wewnetrznej
SN - 0032-3772
IS - 7-8
ER -