Henoch-Schönlein syndrome and cerebellar hemorrhage: Report of an adolescent case and literature review

Sergio Paolini, Pasquale Ciappetta, Maria Cristina Piattella, Maurizio Domenicucci

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Henoch-Schönlein syndrome (HSS) is a systemic necrotizing vasculitis predominantly affecting children. Symptoms are usually self-limited and only rarely do they involve the central nervous system. Only five published reports describe cases of radiologically proven intracranial hemorrhages complicating HSS. CASE DESCRIPTION: In this 17-year-old boy, a cerebellar hemorrhage developed after aspecific symptoms of upper respiratory tract infection. His past medical history and emerging evidence of systemic bleeding yielded a diagnosis of recurrent HSS. This was the fourth time the disease had recurred since the age of 4. The patient underwent surgical treatment and returned to his normal activities. CONCLUSIONS: Intracerebral hemorrhages during HSS share a favorable prognosis and a posterior lobar localization, typically involving the parieto-occipital region. The case described here is unusual because the patient did not have the typical purpuric rash and unlike published cases, the intracranial hemorrhage marked the onset of HSS rather than complicating a typical HSS presentation.

Original languageEnglish
Pages (from-to)339-342
Number of pages4
JournalSurgical Neurology
Volume60
Issue number4
DOIs
Publication statusPublished - Oct 1 2003

Fingerprint

Cerebellar Diseases
Hemorrhage
Intracranial Hemorrhages
Systemic Vasculitis
Occipital Lobe
Cerebral Hemorrhage
Exanthema
Respiratory Tract Infections
Central Nervous System

Keywords

  • Cerebellum
  • Henoch-Schönlein
  • Intracranial hemorrhage

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Henoch-Schönlein syndrome and cerebellar hemorrhage : Report of an adolescent case and literature review. / Paolini, Sergio; Ciappetta, Pasquale; Piattella, Maria Cristina; Domenicucci, Maurizio.

In: Surgical Neurology, Vol. 60, No. 4, 01.10.2003, p. 339-342.

Research output: Contribution to journalArticle

Paolini, Sergio ; Ciappetta, Pasquale ; Piattella, Maria Cristina ; Domenicucci, Maurizio. / Henoch-Schönlein syndrome and cerebellar hemorrhage : Report of an adolescent case and literature review. In: Surgical Neurology. 2003 ; Vol. 60, No. 4. pp. 339-342.
@article{343a37e5973f4e99acf4fcd55f2bae78,
title = "Henoch-Sch{\"o}nlein syndrome and cerebellar hemorrhage: Report of an adolescent case and literature review",
abstract = "BACKGROUND: Henoch-Sch{\"o}nlein syndrome (HSS) is a systemic necrotizing vasculitis predominantly affecting children. Symptoms are usually self-limited and only rarely do they involve the central nervous system. Only five published reports describe cases of radiologically proven intracranial hemorrhages complicating HSS. CASE DESCRIPTION: In this 17-year-old boy, a cerebellar hemorrhage developed after aspecific symptoms of upper respiratory tract infection. His past medical history and emerging evidence of systemic bleeding yielded a diagnosis of recurrent HSS. This was the fourth time the disease had recurred since the age of 4. The patient underwent surgical treatment and returned to his normal activities. CONCLUSIONS: Intracerebral hemorrhages during HSS share a favorable prognosis and a posterior lobar localization, typically involving the parieto-occipital region. The case described here is unusual because the patient did not have the typical purpuric rash and unlike published cases, the intracranial hemorrhage marked the onset of HSS rather than complicating a typical HSS presentation.",
keywords = "Cerebellum, Henoch-Sch{\"o}nlein, Intracranial hemorrhage",
author = "Sergio Paolini and Pasquale Ciappetta and Piattella, {Maria Cristina} and Maurizio Domenicucci",
year = "2003",
month = "10",
day = "1",
doi = "10.1016/S0090-3019(03)00166-6",
language = "English",
volume = "60",
pages = "339--342",
journal = "Surgical Neurology",
issn = "0090-3019",
publisher = "Elsevier BV",
number = "4",

}

TY - JOUR

T1 - Henoch-Schönlein syndrome and cerebellar hemorrhage

T2 - Report of an adolescent case and literature review

AU - Paolini, Sergio

AU - Ciappetta, Pasquale

AU - Piattella, Maria Cristina

AU - Domenicucci, Maurizio

PY - 2003/10/1

Y1 - 2003/10/1

N2 - BACKGROUND: Henoch-Schönlein syndrome (HSS) is a systemic necrotizing vasculitis predominantly affecting children. Symptoms are usually self-limited and only rarely do they involve the central nervous system. Only five published reports describe cases of radiologically proven intracranial hemorrhages complicating HSS. CASE DESCRIPTION: In this 17-year-old boy, a cerebellar hemorrhage developed after aspecific symptoms of upper respiratory tract infection. His past medical history and emerging evidence of systemic bleeding yielded a diagnosis of recurrent HSS. This was the fourth time the disease had recurred since the age of 4. The patient underwent surgical treatment and returned to his normal activities. CONCLUSIONS: Intracerebral hemorrhages during HSS share a favorable prognosis and a posterior lobar localization, typically involving the parieto-occipital region. The case described here is unusual because the patient did not have the typical purpuric rash and unlike published cases, the intracranial hemorrhage marked the onset of HSS rather than complicating a typical HSS presentation.

AB - BACKGROUND: Henoch-Schönlein syndrome (HSS) is a systemic necrotizing vasculitis predominantly affecting children. Symptoms are usually self-limited and only rarely do they involve the central nervous system. Only five published reports describe cases of radiologically proven intracranial hemorrhages complicating HSS. CASE DESCRIPTION: In this 17-year-old boy, a cerebellar hemorrhage developed after aspecific symptoms of upper respiratory tract infection. His past medical history and emerging evidence of systemic bleeding yielded a diagnosis of recurrent HSS. This was the fourth time the disease had recurred since the age of 4. The patient underwent surgical treatment and returned to his normal activities. CONCLUSIONS: Intracerebral hemorrhages during HSS share a favorable prognosis and a posterior lobar localization, typically involving the parieto-occipital region. The case described here is unusual because the patient did not have the typical purpuric rash and unlike published cases, the intracranial hemorrhage marked the onset of HSS rather than complicating a typical HSS presentation.

KW - Cerebellum

KW - Henoch-Schönlein

KW - Intracranial hemorrhage

UR - http://www.scopus.com/inward/record.url?scp=0141626009&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141626009&partnerID=8YFLogxK

U2 - 10.1016/S0090-3019(03)00166-6

DO - 10.1016/S0090-3019(03)00166-6

M3 - Article

C2 - 14505859

AN - SCOPUS:0141626009

VL - 60

SP - 339

EP - 342

JO - Surgical Neurology

JF - Surgical Neurology

SN - 0090-3019

IS - 4

ER -