Heparin surface treatment of poly(methylmethacrylate) alters adhesion of a Staphylococcus aureus strain: utility of bacterial fatty acid analysis

Carla Renata Arciola, Livio Radin, Paola Alvergna, Elisabetta Cenni, Arturo Pizzoferrato

Research output: Contribution to journalArticle

Abstract

Bacterial adhesion on biomaterials is an important cause of associated infection. Many authors have studied the adhesion mechanisms of bacteria on biomaterials. These studies were useful in making materials more and more refractory to bacterial adhesion. We analysed the gas Chromatographie modifications of structural fatty acids of a Staphylococcus aureus strain after adhesion on two polymers, poly(methylmethacrylate) (PMMA), whose biological compatibility is known, and heparin-surface-modified PMMA (HSM-PMMA). We noted changes to the Chromatographie peaks peculiar to the fatty acids of S. aureus for each tested material and particularly for HSM-PMMA.

Original languageEnglish
Pages (from-to)1161-1164
Number of pages4
JournalBiomaterials
Volume14
Issue number15
DOIs
Publication statusPublished - 1993

Keywords

  • Bacterial adhesion
  • fatty acid methyl esters
  • heparinization
  • poly(methylmethacrylate)

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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