Hepatic and renal effects of cardiopulmonary bypass

Research output: Contribution to journalArticlepeer-review


Although associated with low morbidity and mortality, cardiopulmonary bypass remains a "non-physiologic" device that carries a set of complications. Hepatic and renal impairment are associated with a poor outcome. The knowledge of pathophysiology, risk factors and therapeutic interventions can help the anaesthesiologist in preventing these complications in daily practice. The present narrative review provides an update of the literature on the effects of cardiopulmonary bypass on hepatic and renal functions, focussing on markers of hepatic and renal injuries, perioperative strategies in preserving organ function and replacement therapies.

Original languageEnglish
Pages (from-to)151-161
Number of pages11
JournalBest Practice and Research: Clinical Anaesthesiology
Issue number2
Publication statusPublished - 2015


  • acute kidney injury
  • anaesthesia
  • cardiac anaesthesia
  • cardiopulmonary bypass
  • hepatic dysfunction
  • intensive care
  • renal injury
  • shock liver

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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