Abstract
Although associated with low morbidity and mortality, cardiopulmonary bypass remains a "non-physiologic" device that carries a set of complications. Hepatic and renal impairment are associated with a poor outcome. The knowledge of pathophysiology, risk factors and therapeutic interventions can help the anaesthesiologist in preventing these complications in daily practice. The present narrative review provides an update of the literature on the effects of cardiopulmonary bypass on hepatic and renal functions, focussing on markers of hepatic and renal injuries, perioperative strategies in preserving organ function and replacement therapies.
| Original language | English |
|---|---|
| Pages (from-to) | 151-161 |
| Number of pages | 11 |
| Journal | Best Practice and Research: Clinical Anaesthesiology |
| Volume | 29 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2015 |
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Keywords
- acute kidney injury
- anaesthesia
- cardiac anaesthesia
- cardiopulmonary bypass
- hepatic dysfunction
- intensive care
- renal injury
- shock liver
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Hepatic and renal effects of cardiopulmonary bypass. / Di Tomasso, Nora; Monaco, Fabrizio; Landoni, Giovanni.
In: Best Practice and Research: Clinical Anaesthesiology, Vol. 29, No. 2, 2015, p. 151-161.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hepatic and renal effects of cardiopulmonary bypass
AU - Di Tomasso, Nora
AU - Monaco, Fabrizio
AU - Landoni, Giovanni
PY - 2015
Y1 - 2015
N2 - Although associated with low morbidity and mortality, cardiopulmonary bypass remains a "non-physiologic" device that carries a set of complications. Hepatic and renal impairment are associated with a poor outcome. The knowledge of pathophysiology, risk factors and therapeutic interventions can help the anaesthesiologist in preventing these complications in daily practice. The present narrative review provides an update of the literature on the effects of cardiopulmonary bypass on hepatic and renal functions, focussing on markers of hepatic and renal injuries, perioperative strategies in preserving organ function and replacement therapies.
AB - Although associated with low morbidity and mortality, cardiopulmonary bypass remains a "non-physiologic" device that carries a set of complications. Hepatic and renal impairment are associated with a poor outcome. The knowledge of pathophysiology, risk factors and therapeutic interventions can help the anaesthesiologist in preventing these complications in daily practice. The present narrative review provides an update of the literature on the effects of cardiopulmonary bypass on hepatic and renal functions, focussing on markers of hepatic and renal injuries, perioperative strategies in preserving organ function and replacement therapies.
KW - acute kidney injury
KW - anaesthesia
KW - cardiac anaesthesia
KW - cardiopulmonary bypass
KW - hepatic dysfunction
KW - intensive care
KW - renal injury
KW - shock liver
UR - http://www.scopus.com/inward/record.url?scp=84947022330&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84947022330&partnerID=8YFLogxK
U2 - 10.1016/j.bpa.2015.04.001
DO - 10.1016/j.bpa.2015.04.001
M3 - Article
C2 - 26060027
AN - SCOPUS:84947022330
VL - 29
SP - 151
EP - 161
JO - Best Practice and Research in Clinical Anaesthesiology
JF - Best Practice and Research in Clinical Anaesthesiology
SN - 1753-3740
IS - 2
ER -