Hepatic angiosarcoma from vinyl chloride. Report of a new Italian case

G. Chiappino, P. A. Bertazzi, M. Baroni, T. Masini

Research output: Contribution to journalArticle


The fourth case of angiosarcoma of the liver among workers exposed to vinyl chloride in Italy is reported. The case was a 43 yr old man who worked from 1959 to 1980 in a VCM/PVC production plant, mostly in the polymerization area. He died in March 1981, four months after diagnosis, from a massive hemoperitoneum. Post mortem examination was performed. According to four independent pathologists the histologic appearance was typical of a highly deviating angiosarcoma. The tumor developed after a sclerotic liver lesion was already present. The angiosarcoma was probably polycentric, had a high degree of malignancy and a rapid local evolution while, in contrast, no metastases were detected.

Original languageEnglish
Pages (from-to)555-563
Number of pages9
JournalMedicina del Lavoro
Issue number6
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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