Hepatic glutathione content in patients with alcoholic and non alcoholic liver diseases

Emanuele Altomare, Gianluigi Vendemiale, Ottavio Albano

Research output: Contribution to journalArticle

Abstract

Reduced and oxidized hepatic glutathione was evaluated during alcoholic and non alcoholic liver injury. We studied 35 chronic alcoholics, 20 patients with non alcoholic liver diseases, 15 control subjects. Hepatic glutathione was measured in liver biopsies and correlated with histology and laboratory tests. Alcoholic and non alcoholic patients exhibited a significant decrease of hepatic glutathione compared to control subjects (controls: 4.14 ± 0.1 μmol/g liver; alcoholics: 2.55 ± 0.1, p

Original languageEnglish
Pages (from-to)991-998
Number of pages8
JournalLife Sciences
Volume43
Issue number12
DOIs
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Pharmacology

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