Hepatic intra-arterial injection of Yttrium-loaded microspheres for Liver Metastasis secondary to colorectal cancer: Best soups are sometimes made from old recipies

Alain Hendlisz, N. Personeni, Th Delaunoit, S. Debroux, P. Flamen

Research output: Contribution to journalArticle

Abstract

Colorectal cancer is a severe disease with a significant incidence in western world. In the course of disease, about 40% of patients will eventually develop metastases to the liver. The majority of them will never be candidate for curative surgical management. For those patients, systemic or intra-hepatic chemotherapy is the treatment's cornerstone. Unfortunately, despite evident improvements and apparition of several active new agents, no hope of cure emerges on the agenda for now. Hepatic intra-arterial injections of radioactive devices have since a long time drawn interest from the medical community. An anti-tumoural activity has been demonstrated with Yttrium-loaded microspheres injected in the hepatic artery for several liver neoplasms including metastases from colorectal cancer. We lack however the results of large randomized phase III trials to define clearly the place of those interventional therapies in the management of colorectal cancer metastatic to the liver.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalActa Gastro-Enterologica Belgica
Volume69
Issue number1
Publication statusPublished - Jan 2006

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Intra-Arterial Injections
Yttrium
Microspheres
Colorectal Neoplasms
Neoplasm Metastasis
Liver
Western World
Hepatic Artery
Liver Neoplasms
Drug Therapy
Equipment and Supplies
Incidence
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

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Hepatic intra-arterial injection of Yttrium-loaded microspheres for Liver Metastasis secondary to colorectal cancer : Best soups are sometimes made from old recipies. / Hendlisz, Alain; Personeni, N.; Delaunoit, Th; Debroux, S.; Flamen, P.

In: Acta Gastro-Enterologica Belgica, Vol. 69, No. 1, 01.2006, p. 55-58.

Research output: Contribution to journalArticle

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