Hepatic pseudocystic metastasis of well-differentiated ileal neuroendocrine tumor: A case report with review of the literature

Stefano Fiori, Alessandro Del Gobbo, Gabriella Gaudioso, Lucio Caccamo, Sara Massironi, Federica Cavalcoli, Silvano Bosari, Stefano Ferrero

Research output: Contribution to journalArticle


Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystadenomas and eventually to primary or metastatic malignancies.Primary or metastatic hepatic malignancies with pseudocystic aspects are rare, and a pseudocystic aspect is reported only after neo-adjuvant treatment.Liver metastasis of untreated neuroendocrine tumors are usually solid and, to our knowledge, only two cases of neuroendocrine cystic hepatic metastases of ileal atypical carcinoids have been reported so far.We present a case of a 67 years old man with synchronous finding of an untreated hepatic pseudocystic lesion and an ileal mass histologically diagnosed as a well differentiated (G1) neuroendocrine tumor. The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1443883503102967.

Original languageEnglish
Article number148
JournalDiagnostic Pathology
Issue number1
Publication statusPublished - Sep 13 2013



  • Hepatic malignancies
  • Neuroendocrine tumor
  • Pseudocystic metastasis

ASJC Scopus subject areas

  • Histology
  • Pathology and Forensic Medicine

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