TY - JOUR
T1 - Hepatic resection for "bCLC Stage A" hepatocellular carcinoma. the prognostic role of alpha-fetoprotein
AU - Santambrogio, Roberto
AU - Opocher, Enrico
AU - Costa, Mara
AU - Barabino, Matteo
AU - Zuin, Massimo
AU - Bertolini, Emanuela
AU - De Filippi, Francesca
AU - Bruno, Savino
PY - 2012/2
Y1 - 2012/2
N2 - Background: Our aim was to assess the capability of Barcelona Clinic Liver Cancer (BCLC) staging system in allocating stage A patients to hepatic resection (HR) and the effect on survival. Methods: We enrolled 132 patients with hepatocellular carcinoma (HCC) amenable to HR. All patients underwent ultrasound (US)-guided anatomical resection (≤2 segments) and then postoperative results were evaluated. Results: Results showed 95% of patients were Child A, 49% in BCLC A1, 21% in A2, 6% in A3, and 24% in A4. No 30-day mortality occurred. Overall survival got worse from A1 to A4 (P = 0.0271), while no differences were found in Childs A patients with or without portal hypertension (P = 0.1674). Multivariate analysis (Cox model) shows that only AFP (
AB - Background: Our aim was to assess the capability of Barcelona Clinic Liver Cancer (BCLC) staging system in allocating stage A patients to hepatic resection (HR) and the effect on survival. Methods: We enrolled 132 patients with hepatocellular carcinoma (HCC) amenable to HR. All patients underwent ultrasound (US)-guided anatomical resection (≤2 segments) and then postoperative results were evaluated. Results: Results showed 95% of patients were Child A, 49% in BCLC A1, 21% in A2, 6% in A3, and 24% in A4. No 30-day mortality occurred. Overall survival got worse from A1 to A4 (P = 0.0271), while no differences were found in Childs A patients with or without portal hypertension (P = 0.1674). Multivariate analysis (Cox model) shows that only AFP (
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U2 - 10.1245/s10434-011-1845-6
DO - 10.1245/s10434-011-1845-6
M3 - Article
C2 - 21732145
AN - SCOPUS:84856649829
VL - 19
SP - 426
EP - 434
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
SN - 1068-9265
IS - 2
ER -