Hepatic sonography in the evaluation of potential multi-organ donors

F. Draghi, A. Spinazzola, D. Abbati, M. Precerutti, C. Fachinetti

Research output: Contribution to journalArticle

Abstract

Purpose: The aim of the present study was to evaluate the usefulness and the limits of pre-explant ultrasonography of the liver in the workup of multi-organ donor patients. Methods and materials: Between January 2001 and March 2004, 52 sonographic examinations of the liver were performed on potential multi-organ donors aged 2-72 years (mean: 45.3). In all cases, the cause of death was cerebral hemorrhage/ischemia (spontaneous or traumatic). The examinations included evaluation of the echo-texture of the liver, the presence or the absence of focal lesions or diffuse disease, vascularity, and the biliary tract. Results: In one patient, three hepatic cysts were found, three presented solid hyperechoic lesions that were later confirmed to be hemangiomas by pre-implant histologic examination, and 18 patients were found to have diffuse chronic liver disease. In four of these cases, the sonographic diagnosis was not concordant with the results of the biopsy examination. Conclusion: Ultrasonography can be considered a reliable method for detecting focal liver lesions in potential organ donors. Distinguishing between benign and malignant lesions on the basis of sonographic findings is not required since this can be accomplished during the routine biopsy examination. It is also reliable for the evaluation of vascularity and the biliary tract, but it was of limited use in defining the nature and severity of chronic diffuse liver disease.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalJournal of Ultrasound
Volume10
Issue number1
DOIs
Publication statusPublished - Mar 2007

Fingerprint

Ultrasonography
Tissue Donors
Liver
Liver Diseases
Biliary Tract Diseases
Biopsy
Cerebral Hemorrhage
Biliary Tract
Hemangioma
Brain Ischemia
Cysts
Cause of Death
Chronic Disease

Keywords

  • Liver
  • Sonography
  • Transplant

ASJC Scopus subject areas

  • Internal Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Hepatic sonography in the evaluation of potential multi-organ donors. / Draghi, F.; Spinazzola, A.; Abbati, D.; Precerutti, M.; Fachinetti, C.

In: Journal of Ultrasound, Vol. 10, No. 1, 03.2007, p. 1-4.

Research output: Contribution to journalArticle

Draghi, F, Spinazzola, A, Abbati, D, Precerutti, M & Fachinetti, C 2007, 'Hepatic sonography in the evaluation of potential multi-organ donors', Journal of Ultrasound, vol. 10, no. 1, pp. 1-4. https://doi.org/10.1016/j.jus.2007.02.003
Draghi, F. ; Spinazzola, A. ; Abbati, D. ; Precerutti, M. ; Fachinetti, C. / Hepatic sonography in the evaluation of potential multi-organ donors. In: Journal of Ultrasound. 2007 ; Vol. 10, No. 1. pp. 1-4.
@article{c23e1a8e5f5b4683956aaf78e1d3c9e7,
title = "Hepatic sonography in the evaluation of potential multi-organ donors",
abstract = "Purpose: The aim of the present study was to evaluate the usefulness and the limits of pre-explant ultrasonography of the liver in the workup of multi-organ donor patients. Methods and materials: Between January 2001 and March 2004, 52 sonographic examinations of the liver were performed on potential multi-organ donors aged 2-72 years (mean: 45.3). In all cases, the cause of death was cerebral hemorrhage/ischemia (spontaneous or traumatic). The examinations included evaluation of the echo-texture of the liver, the presence or the absence of focal lesions or diffuse disease, vascularity, and the biliary tract. Results: In one patient, three hepatic cysts were found, three presented solid hyperechoic lesions that were later confirmed to be hemangiomas by pre-implant histologic examination, and 18 patients were found to have diffuse chronic liver disease. In four of these cases, the sonographic diagnosis was not concordant with the results of the biopsy examination. Conclusion: Ultrasonography can be considered a reliable method for detecting focal liver lesions in potential organ donors. Distinguishing between benign and malignant lesions on the basis of sonographic findings is not required since this can be accomplished during the routine biopsy examination. It is also reliable for the evaluation of vascularity and the biliary tract, but it was of limited use in defining the nature and severity of chronic diffuse liver disease.",
keywords = "Liver, Sonography, Transplant",
author = "F. Draghi and A. Spinazzola and D. Abbati and M. Precerutti and C. Fachinetti",
year = "2007",
month = "3",
doi = "10.1016/j.jus.2007.02.003",
language = "English",
volume = "10",
pages = "1--4",
journal = "Journal of Ultrasound",
issn = "1971-3495",
publisher = "Elsevier Masson SAS",
number = "1",

}

TY - JOUR

T1 - Hepatic sonography in the evaluation of potential multi-organ donors

AU - Draghi, F.

AU - Spinazzola, A.

AU - Abbati, D.

AU - Precerutti, M.

AU - Fachinetti, C.

PY - 2007/3

Y1 - 2007/3

N2 - Purpose: The aim of the present study was to evaluate the usefulness and the limits of pre-explant ultrasonography of the liver in the workup of multi-organ donor patients. Methods and materials: Between January 2001 and March 2004, 52 sonographic examinations of the liver were performed on potential multi-organ donors aged 2-72 years (mean: 45.3). In all cases, the cause of death was cerebral hemorrhage/ischemia (spontaneous or traumatic). The examinations included evaluation of the echo-texture of the liver, the presence or the absence of focal lesions or diffuse disease, vascularity, and the biliary tract. Results: In one patient, three hepatic cysts were found, three presented solid hyperechoic lesions that were later confirmed to be hemangiomas by pre-implant histologic examination, and 18 patients were found to have diffuse chronic liver disease. In four of these cases, the sonographic diagnosis was not concordant with the results of the biopsy examination. Conclusion: Ultrasonography can be considered a reliable method for detecting focal liver lesions in potential organ donors. Distinguishing between benign and malignant lesions on the basis of sonographic findings is not required since this can be accomplished during the routine biopsy examination. It is also reliable for the evaluation of vascularity and the biliary tract, but it was of limited use in defining the nature and severity of chronic diffuse liver disease.

AB - Purpose: The aim of the present study was to evaluate the usefulness and the limits of pre-explant ultrasonography of the liver in the workup of multi-organ donor patients. Methods and materials: Between January 2001 and March 2004, 52 sonographic examinations of the liver were performed on potential multi-organ donors aged 2-72 years (mean: 45.3). In all cases, the cause of death was cerebral hemorrhage/ischemia (spontaneous or traumatic). The examinations included evaluation of the echo-texture of the liver, the presence or the absence of focal lesions or diffuse disease, vascularity, and the biliary tract. Results: In one patient, three hepatic cysts were found, three presented solid hyperechoic lesions that were later confirmed to be hemangiomas by pre-implant histologic examination, and 18 patients were found to have diffuse chronic liver disease. In four of these cases, the sonographic diagnosis was not concordant with the results of the biopsy examination. Conclusion: Ultrasonography can be considered a reliable method for detecting focal liver lesions in potential organ donors. Distinguishing between benign and malignant lesions on the basis of sonographic findings is not required since this can be accomplished during the routine biopsy examination. It is also reliable for the evaluation of vascularity and the biliary tract, but it was of limited use in defining the nature and severity of chronic diffuse liver disease.

KW - Liver

KW - Sonography

KW - Transplant

UR - http://www.scopus.com/inward/record.url?scp=34250714449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250714449&partnerID=8YFLogxK

U2 - 10.1016/j.jus.2007.02.003

DO - 10.1016/j.jus.2007.02.003

M3 - Article

VL - 10

SP - 1

EP - 4

JO - Journal of Ultrasound

JF - Journal of Ultrasound

SN - 1971-3495

IS - 1

ER -