Hepatic spleen nodules (HSN)

Claudia Mescoli, Carlo Castoro, Adriana Sergio, Alberto Ruol, Fabio Farinati, Massimo Rugge

Research output: Contribution to journalArticlepeer-review


Hepatic splenosis is a nodular implant of normal spleen tissue in the liver. This innocent liver nodule is frequently misinterpreted as a malignancy. Almost all hepatic splenoses have been associated with a clinical history of splenic trauma or prior surgery. This report describes two cases of hepatic splenosis. In both patients, the nodular lesions were initially thought to be liver malignancies and they were ultimately assessed by histology. The clinico-pathological findings of all published cases of liver splenosis underwent critical review. Although they are rare, hepatic spleen nodules should always be included in the diagnostic spectrum of nodular liver lesions because of their impact on treatment decisions.

Original languageEnglish
Pages (from-to)628-632
Number of pages5
JournalScandinavian Journal of Gastroenterology
Issue number5
Publication statusPublished - May 2010


  • Granulomatous hepatitis
  • Hepatic splenosis
  • Splenic angioma

ASJC Scopus subject areas

  • Gastroenterology

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