Abstract
The hepatocyte is traditionally considered as the cell responsible for liver regeneration, being able to enter in cell cycle and to restore hepatic parenchyma. However, a stem cell compartment (so called "oval cells") is activated in response to injury when the proliferative capacity of the hepatocyte is altered. Recent studies suggest that at least a subpopulation of oval cells may originate from bone marrow-derived stem cells. Such observations can have an important impact both on theories concerning cell differentiation and on cell therapy in liver disease.
| Translated title of the contribution | Hepatic stem cells |
|---|---|
| Original language | Italian |
| Pages (from-to) | 3-11 |
| Number of pages | 9 |
| Journal | Argomenti di Gastroenterologia Clinica |
| Volume | 17 |
| Issue number | 1 |
| Publication status | Published - Mar 2004 |
ASJC Scopus subject areas
- Gastroenterology