Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit

L. Ghio, G. A. Moroni, P. Piccoli, M. Trombini, M. Giani, M. Angeli, A. Edefonti

Research output: Contribution to journalArticle

Abstract

Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.

Original languageEnglish
Pages (from-to)17-26
Number of pages10
JournalHelvetica Paediatrica Acta
Volume37
Issue number1
Publication statusPublished - 1982

Fingerprint

Hepatitis B
Hepatitis B virus
Renal Dialysis
Immunoglobulins
Pediatrics
Active Immunity
Hepatitis B e Antigens
Diuresis
Hepatitis B Surface Antigens
Chronic Kidney Failure
Needles
Urine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit. / Ghio, L.; Moroni, G. A.; Piccoli, P.; Trombini, M.; Giani, M.; Angeli, M.; Edefonti, A.

In: Helvetica Paediatrica Acta, Vol. 37, No. 1, 1982, p. 17-26.

Research output: Contribution to journalArticle

Ghio, L. ; Moroni, G. A. ; Piccoli, P. ; Trombini, M. ; Giani, M. ; Angeli, M. ; Edefonti, A. / Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit. In: Helvetica Paediatrica Acta. 1982 ; Vol. 37, No. 1. pp. 17-26.
@article{e22570a7459144f3b350615865e66953,
title = "Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit",
abstract = "Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.",
author = "L. Ghio and Moroni, {G. A.} and P. Piccoli and M. Trombini and M. Giani and M. Angeli and A. Edefonti",
year = "1982",
language = "English",
volume = "37",
pages = "17--26",
journal = "Helvetica Paediatrica Acta",
issn = "0018-022X",
publisher = "Schwabe und Co. AG",
number = "1",

}

TY - JOUR

T1 - Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit

AU - Ghio, L.

AU - Moroni, G. A.

AU - Piccoli, P.

AU - Trombini, M.

AU - Giani, M.

AU - Angeli, M.

AU - Edefonti, A.

PY - 1982

Y1 - 1982

N2 - Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.

AB - Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.

UR - http://www.scopus.com/inward/record.url?scp=0020075412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020075412&partnerID=8YFLogxK

M3 - Article

C2 - 7085327

AN - SCOPUS:0020075412

VL - 37

SP - 17

EP - 26

JO - Helvetica Paediatrica Acta

JF - Helvetica Paediatrica Acta

SN - 0018-022X

IS - 1

ER -