Hepatitis B prevalence and immunoprophylaxis with hepatitis B immunoglobulins in patients, relatives, and staff of a paediatric haemodialysis unit

L. Ghio, G. A. Moroni, P. Piccoli, M. Trombini, M. Giani, M. Angeli, A. Edefonti

Research output: Contribution to journalArticlepeer-review

Abstract

Hepatitis B virus (HBV) markers have been studied for 22 months in 16 haemodialysed patients, 60 relatives and 17 staff members of a paediatric haemodialysis unit, and in 9 children with chronic renal failure on conservative therapy. None of the 8 children negative for HBV markers and treated with specific immunoglobulins (HBIG) developed signs of hepatitis B. No hepatitis B occurred in 4 staff members after accidental infected needle prick and immunoprophylaxis, although one of them developed passive-active immunity. The immunoprophylaxis effectively prevented diffusion of HBV also in the relatives. Furthermore, HBsAg and HBeAg were found in urine samples of haemodialysed children with residual diuresis.

Original languageEnglish
Pages (from-to)17-26
Number of pages10
JournalHelvetica Paediatrica Acta
Volume37
Issue number1
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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