Hepatitis B virus-related markers in secondary and in essential mixed cryoglobulinemias: A multicentric study of 596 cases

M. Galli, G. Monti, F. Invernizzi, A. Monteverde, S. Bombardieri, A. Gabrielli, S. Migliaresi, C. Mussini, E. Ossi, M. Pietrogrande, L. Quintiliani, P. Renoldi, A. Vacca, F. Saccardo, C. Ferri, G. Bordin, C. Mazzaro, S. Rusconi

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to assess the prevalence of HBV-related markers in cryoglobulinemias and the possible association between hepatitis B virus (HBV) and essential mixed cryoglobulinemia (EMC). A retrospective survey of the prevalence of HBV infection in cryoglobulinemic patients was carried out in 596 cases of cryoglobulinemia. On the basis of clinical and laboratory criteria the cases were grouped as secondary to connective tissue disease, to lymphoprolipherative disorders, to chronic liver diseases or to chronic infectious diseases. The cases in which an associated disease was not evidenced were considered as essential mixed cryogobulinemias. Subjects in which liver dysfunction was first diagnosed simultaneously with cryoglobulinemia, were considered as a separate group. A greater prevalence of HBsAg and anti-HBc antibodies was found in cryoglobulinemias secondary to chronic liver disease (p

Original languageEnglish
Pages (from-to)209-214
Number of pages6
JournalAnnali Italiani di Medicina Interna
Volume7
Issue number4
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Internal Medicine

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