Hepatitis C infection in patients with chronic kidney disease

A. Mangia; P. Burra; A. Ciancio; S. Fagiuoli; M. Guido; A. Picciotto; F. Fabrizi

Hepatitis C infection in patients with chronic kidney disease

A. Mangia, P. Burra, A. Ciancio, S. Fagiuoli, M. Guido, A. Picciotto, F. Fabrizi

Research output: Contribution to journal › Article › peer-review

Abstract

The management of hepatitis C virus (HCV)-infected patients with chronic kidney disease (CKD) is complex and represents a particular concern since numerous issues, such as antiviral therapy in dialysis patients and post renal transplant, and prevention of HCV spread within dialysis units, remain unresolved. An enormous body of literature has been published on HCV in the CKD population; however, clinical evidence on important issues is mostly based on uncontrolled clinical trials or retrospective surveys. The aim of this paper is to provide a systematic review of the literature. Responses to the critical issues have been developed by a consensus of experts, endorsed by the Italian Association for the Study of the Liver (AISF) and some clinical recommendations have been added.

Original language	English
Pages (from-to)	15-33
Number of pages	19
Journal	International Journal of Artificial Organs
Volume	31
Issue number	1
Publication status	Published - Jan 2008

Keywords

Chronic kidney disease
Dialysis
Hepatitis C
Renal transplantation

ASJC Scopus subject areas

Biophysics

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AU - Burra, P.

AU - Ciancio, A.

AU - Fagiuoli, S.

AU - Guido, M.

AU - Picciotto, A.

AU - Fabrizi, F.

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AB - The management of hepatitis C virus (HCV)-infected patients with chronic kidney disease (CKD) is complex and represents a particular concern since numerous issues, such as antiviral therapy in dialysis patients and post renal transplant, and prevention of HCV spread within dialysis units, remain unresolved. An enormous body of literature has been published on HCV in the CKD population; however, clinical evidence on important issues is mostly based on uncontrolled clinical trials or retrospective surveys. The aim of this paper is to provide a systematic review of the literature. Responses to the critical issues have been developed by a consensus of experts, endorsed by the Italian Association for the Study of the Liver (AISF) and some clinical recommendations have been added.

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KW - Hepatitis C

KW - Renal transplantation

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