Hepatitis C: Is eradication possible?

ESCMID Study Group for Viral Hepatitis (ESGVH)

Research output: Contribution to journalArticlepeer-review


Hepatitis C has a relevant global impact in terms of morbidity, mortality and economic costs, with more than 70 million people infected worldwide. In the resolution, “Transforming our world: the 2030 Agenda for Sustainable Development” was included as a focus area in the health-related goal with world leaders pledging to “combat” it by 2030. In response, WHO drafted the Global Viral Hepatitis Strategy carrying the ambitious targets to reduce the number of deaths by two-thirds and to increase treatment rates up to 80%. Despite the availability of highly effective therapeutic regimens based on direct-acting antivirals many barriers to HCV eradication still remain. They are related to awareness of the infection, linkage to care, availability of the therapeutic drug regimens and reinfection. Overall, if an effective prophylactic vaccine will not be available, HCV eradication appears difficult to achieve in the future.

Original languageEnglish
JournalLiver International
Publication statusAccepted/In press - Jan 1 2019


  • DAA
  • HCV
  • HCV-vaccine
  • linkage to care
  • viral eradication

ASJC Scopus subject areas

  • Hepatology


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