Hepatitis C virus infection in patients with non-Hodgkin's lymphoma

C. Ferri, F. Caracciolo, A. L. Zignego, L. La Civita, M. Monti, G. Longombardo, F. Lombardini, F. Greco, E. Capochiani, A. Mazzoni, C. Mazzaro, G. Pasero

Research output: Contribution to journalArticlepeer-review


Hepatitis C virus (HCV), which is both a hepatotropic and a lymphotropic virus, has been proposed as a possible causative agent of mixed cryoglobulinaemia. This 'benign' lymphoproliferative disorder can switch over to a malignant B-cell non-Hodgkin's lymphoma (NHL). Therefore HCV infection has been investigated in a series of 50 unselected Italian patients with B-cell NHL. Antibodies against HCV were found in 30% of NHL and HCV viraemia in 32% of cases. HCV-related markers were detected in 34% (17/50) of our NHL patients; this prevalence is particularly significant when compared with HCV seropositivity in Hodgkin's lymphoma (3%) and healthy controls (1.3%).

Original languageEnglish
Pages (from-to)392-394
Number of pages3
JournalBritish Journal of Haematology
Issue number2
Publication statusPublished - 1994


  • hepatitis C virus
  • non-Hodgkin's lymphoma B-cell lymphoma

ASJC Scopus subject areas

  • Hematology


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