Hepatitis viruses exploitation of host DNA methyltransferases functions

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell’s pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.

Original languageEnglish
JournalClinical and Experimental Medicine
DOIs
Publication statusAccepted/In press - Jul 7 2015

Fingerprint

Hepatitis Viruses
Methyltransferases
Viruses
Hepatitis B virus
Hepacivirus
Protein Methyltransferases
Hepatitis D
Manuscripts
DNA
Liver Neoplasms
Epigenomics
Liver Cirrhosis
Infection
Liver
Health
Global Health

Keywords

  • DNMTs
  • Epigenetics
  • Hepatitis viruses
  • Interferon

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell’s pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.",
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author = "Valerio Pazienza and Concetta Panebianco and Angelo Andriulli",
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AU - Andriulli, Angelo

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AB - Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell’s pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.

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KW - Interferon

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