Hepatoblastoma and familial adenomatous polyposis

J. E. Garber, F. P. Li, J. E. Kingston, A. J. Krush, L. C. Strong, M. J. Finegold, L. Bertario, S. Bülow, A. Filippone, T. Gedde-dahl, H. J. Järvinen

Research output: Contribution to journalArticle

Abstract

Eleven children have been identified as having hepatoblastoma and a family history of adenomatous polyposis, and 14 additional instances of this association have been collected from the literature. Among the 11 survivors of hepatoblastoma in the combined series, adenomatous lesions have been sought in seven and detected in six patients at ages 7 to 25 years. Five of these patients also have congenital hypertrophy of the rential pigment epithelium, a marker for carriers of the polyposis gene. These findings strengthen the association between hepatoblastoma and familial adenomatous polyposis and have led to the establishment of the Hepatoblastoma-Adenomatous Polyposis Registry.

Original languageEnglish
Pages (from-to)1626-1628
Number of pages3
JournalJournal of the National Cancer Institute
Volume80
Issue number20
DOIs
Publication statusPublished - Dec 21 1988

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Oncology
  • Cancer Research

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  • Cite this

    Garber, J. E., Li, F. P., Kingston, J. E., Krush, A. J., Strong, L. C., Finegold, M. J., Bertario, L., Bülow, S., Filippone, A., Gedde-dahl, T., & Järvinen, H. J. (1988). Hepatoblastoma and familial adenomatous polyposis. Journal of the National Cancer Institute, 80(20), 1626-1628. https://doi.org/10.1093/jnci/80.20.1626