Il carcinoma epatocellulare

Chronic hepatitis B and C, alcohol abuse, non alcoholic fatty liver disease, diabetes, aflatoxin, are the most common risk factor of hepatocellular carcinoma (HCC). Independently to the etiology, cirrhosis is the leading cause of HCC, which is the first cause of death in cirrhotic patients. Surveillance of patients t risk, aimed to the early diagnosis of HCC, is the only practical approach to reduce mortality, offering radical therapies. A correct staging of patients, which takes into account liver function, number and size of the liver tumor nodules, patient performance status and coexisting morbidities, is the only way to a correct management of these patients.