Hepatopulmonary syndrome: A review of the literature

G. Ghittoni, G. Valentini, C. Spada, Z. Rossi, G. Gasbarrini

Research output: Contribution to journalArticle

Abstract

The majority of cirrhotic patients present dyspnea, but most of the time this is a consequence of ascites, hepatic hydrothorax or cardiopulmonary disease. Very few of these patients undergo the hepatopulmonary syndrome, an infrequent complication of chronic liver disease, especially when associated with portal hypertension and cirrhosis. Hepatopulmonary syndrome is characterised by dyspnea and, consequently, arterial hypoxemia, due to intrapulmonary vasodilation and shunting. The real pathogenesis of this vasodilation is still unknown, although many hypotheses have been suggested. Furthermore, no medical therapy appears to be really useful in the treatment of hepatopulmonary syndrome. At the present time, the only treatment that is efficacious for the resolution, or for the improvement of blood gas oxygenation abnormalities, is orthotopic liver transplantation.

Original languageEnglish
Pages (from-to)95-98
Number of pages4
JournalPanminerva Medica
Volume45
Issue number2
Publication statusPublished - Jun 2003

Fingerprint

Hepatopulmonary Syndrome
Vasodilation
Dyspnea
Hydrothorax
Portal Hypertension
Ascites
Liver Transplantation
Liver Diseases
Fibrosis
Chronic Disease
Therapeutics
Gases
Liver

Keywords

  • Diagnosis
  • Hepatopulmonary syndrome
  • Hepatopulmonary syndrome, therapy
  • Liver cirrhosis
  • Liver diseases

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ghittoni, G., Valentini, G., Spada, C., Rossi, Z., & Gasbarrini, G. (2003). Hepatopulmonary syndrome: A review of the literature. Panminerva Medica, 45(2), 95-98.

Hepatopulmonary syndrome : A review of the literature. / Ghittoni, G.; Valentini, G.; Spada, C.; Rossi, Z.; Gasbarrini, G.

In: Panminerva Medica, Vol. 45, No. 2, 06.2003, p. 95-98.

Research output: Contribution to journalArticle

Ghittoni, G, Valentini, G, Spada, C, Rossi, Z & Gasbarrini, G 2003, 'Hepatopulmonary syndrome: A review of the literature', Panminerva Medica, vol. 45, no. 2, pp. 95-98.
Ghittoni G, Valentini G, Spada C, Rossi Z, Gasbarrini G. Hepatopulmonary syndrome: A review of the literature. Panminerva Medica. 2003 Jun;45(2):95-98.
Ghittoni, G. ; Valentini, G. ; Spada, C. ; Rossi, Z. ; Gasbarrini, G. / Hepatopulmonary syndrome : A review of the literature. In: Panminerva Medica. 2003 ; Vol. 45, No. 2. pp. 95-98.
@article{779f22da52e7460ebc43cc06fce77f2a,
title = "Hepatopulmonary syndrome: A review of the literature",
abstract = "The majority of cirrhotic patients present dyspnea, but most of the time this is a consequence of ascites, hepatic hydrothorax or cardiopulmonary disease. Very few of these patients undergo the hepatopulmonary syndrome, an infrequent complication of chronic liver disease, especially when associated with portal hypertension and cirrhosis. Hepatopulmonary syndrome is characterised by dyspnea and, consequently, arterial hypoxemia, due to intrapulmonary vasodilation and shunting. The real pathogenesis of this vasodilation is still unknown, although many hypotheses have been suggested. Furthermore, no medical therapy appears to be really useful in the treatment of hepatopulmonary syndrome. At the present time, the only treatment that is efficacious for the resolution, or for the improvement of blood gas oxygenation abnormalities, is orthotopic liver transplantation.",
keywords = "Diagnosis, Hepatopulmonary syndrome, Hepatopulmonary syndrome, therapy, Liver cirrhosis, Liver diseases",
author = "G. Ghittoni and G. Valentini and C. Spada and Z. Rossi and G. Gasbarrini",
year = "2003",
month = "6",
language = "English",
volume = "45",
pages = "95--98",
journal = "Panminerva Medica",
issn = "0031-0808",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "2",

}

TY - JOUR

T1 - Hepatopulmonary syndrome

T2 - A review of the literature

AU - Ghittoni, G.

AU - Valentini, G.

AU - Spada, C.

AU - Rossi, Z.

AU - Gasbarrini, G.

PY - 2003/6

Y1 - 2003/6

N2 - The majority of cirrhotic patients present dyspnea, but most of the time this is a consequence of ascites, hepatic hydrothorax or cardiopulmonary disease. Very few of these patients undergo the hepatopulmonary syndrome, an infrequent complication of chronic liver disease, especially when associated with portal hypertension and cirrhosis. Hepatopulmonary syndrome is characterised by dyspnea and, consequently, arterial hypoxemia, due to intrapulmonary vasodilation and shunting. The real pathogenesis of this vasodilation is still unknown, although many hypotheses have been suggested. Furthermore, no medical therapy appears to be really useful in the treatment of hepatopulmonary syndrome. At the present time, the only treatment that is efficacious for the resolution, or for the improvement of blood gas oxygenation abnormalities, is orthotopic liver transplantation.

AB - The majority of cirrhotic patients present dyspnea, but most of the time this is a consequence of ascites, hepatic hydrothorax or cardiopulmonary disease. Very few of these patients undergo the hepatopulmonary syndrome, an infrequent complication of chronic liver disease, especially when associated with portal hypertension and cirrhosis. Hepatopulmonary syndrome is characterised by dyspnea and, consequently, arterial hypoxemia, due to intrapulmonary vasodilation and shunting. The real pathogenesis of this vasodilation is still unknown, although many hypotheses have been suggested. Furthermore, no medical therapy appears to be really useful in the treatment of hepatopulmonary syndrome. At the present time, the only treatment that is efficacious for the resolution, or for the improvement of blood gas oxygenation abnormalities, is orthotopic liver transplantation.

KW - Diagnosis

KW - Hepatopulmonary syndrome

KW - Hepatopulmonary syndrome, therapy

KW - Liver cirrhosis

KW - Liver diseases

UR - http://www.scopus.com/inward/record.url?scp=0141484432&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141484432&partnerID=8YFLogxK

M3 - Article

C2 - 12855933

AN - SCOPUS:0141484432

VL - 45

SP - 95

EP - 98

JO - Panminerva Medica

JF - Panminerva Medica

SN - 0031-0808

IS - 2

ER -