Epatossicita' della ciclofosfamide dopo trattamento protratto nei ratti: studio istomorfologico.

C. Gismondi; L. Dabove; M. Dovì; A. Picciotto; V. Savarino; R. Testa; C. Mansi

Epatossicita' della ciclofosfamide dopo trattamento protratto nei ratti: studio istomorfologico.

Translated title of the contribution: Hepatotoxicity of cyclophosphamide in the rat after prolonged treatment: a histomorphological study

C. Gismondi, L. Dabove, M. Dovì, A. Picciotto, V. Savarino, R. Testa, C. Mansi

Research output: Contribution to journal › Article › peer-review

Abstract

The AA. have examined the toxic effects in rats liver caused by cyclophosphamide (12 mg/kg) chronic administration for 12 months. The toxicity for the liver is moderate and the lesions are not specific. The lesion are various histologic changes, lymphomonocytic infiltration of the peri-portal space, periportal fibrosis and interstitial haemorrhages. Similar lesions with lesser recurrence are also in not treated rats.

Translated title of the contribution	Hepatotoxicity of cyclophosphamide in the rat after prolonged treatment: a histomorphological study
Original language	Italian
Pages (from-to)	2166-2172
Number of pages	7
Journal	Bollettino della Societa Italiana di Biologia Sperimentale
Volume	56
Issue number	21
Publication status	Published - Nov 15 1980

ASJC Scopus subject areas

Medicine(all)

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Cite this

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title = "Epatossicita' della ciclofosfamide dopo trattamento protratto nei ratti: studio istomorfologico.",

abstract = "The AA. have examined the toxic effects in rats liver caused by cyclophosphamide (12 mg/kg) chronic administration for 12 months. The toxicity for the liver is moderate and the lesions are not specific. The lesion are various histologic changes, lymphomonocytic infiltration of the peri-portal space, periportal fibrosis and interstitial haemorrhages. Similar lesions with lesser recurrence are also in not treated rats.",

author = "C. Gismondi and L. Dabove and M. Dov{\`i} and A. Picciotto and V. Savarino and R. Testa and C. Mansi",

year = "1980",

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journal = "Bollettino della Societa Italiana di Biologia Sperimentale",

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number = "21",

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T1 - Epatossicita' della ciclofosfamide dopo trattamento protratto nei ratti

T2 - studio istomorfologico.

AU - Gismondi, C.

AU - Dabove, L.

AU - Dovì, M.

AU - Picciotto, A.

AU - Savarino, V.

AU - Testa, R.

AU - Mansi, C.

PY - 1980/11/15

Y1 - 1980/11/15

N2 - The AA. have examined the toxic effects in rats liver caused by cyclophosphamide (12 mg/kg) chronic administration for 12 months. The toxicity for the liver is moderate and the lesions are not specific. The lesion are various histologic changes, lymphomonocytic infiltration of the peri-portal space, periportal fibrosis and interstitial haemorrhages. Similar lesions with lesser recurrence are also in not treated rats.

AB - The AA. have examined the toxic effects in rats liver caused by cyclophosphamide (12 mg/kg) chronic administration for 12 months. The toxicity for the liver is moderate and the lesions are not specific. The lesion are various histologic changes, lymphomonocytic infiltration of the peri-portal space, periportal fibrosis and interstitial haemorrhages. Similar lesions with lesser recurrence are also in not treated rats.

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M3 - Articolo

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AN - SCOPUS:0019326356

VL - 56

SP - 2166

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JO - Bollettino della Societa Italiana di Biologia Sperimentale

JF - Bollettino della Societa Italiana di Biologia Sperimentale

SN - 0037-8771

IS - 21

ER -