HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature

Arpine Gevorgyan; Giacomo Bregni; Giulia Galli; Elisa Zanardi; Filippo De Braud; Serena Di Cosimo

doi:10.1159/000453572

HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature

Arpine Gevorgyan, Giacomo Bregni, Giulia Galli, Elisa Zanardi, Filippo De Braud, Serena Di Cosimo

Research output: Contribution to journal › Review article › peer-review

Abstract

Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.

Original language	English
Pages (from-to)	424-426
Number of pages	3
Journal	Breast Care
Volume	11
Issue number	6
DOIs	https://doi.org/10.1159/000453572
Publication status	Published - Dec 1 2016

Keywords

Breast carcinoma
Neuroendocrine carcinoma
Trastuzumab

ASJC Scopus subject areas

Surgery
Oncology

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10.1159/000453572

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title = "HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature",

abstract = "Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.",

keywords = "Breast carcinoma, Neuroendocrine carcinoma, Trastuzumab",

author = "Arpine Gevorgyan and Giacomo Bregni and Giulia Galli and Elisa Zanardi and {De Braud}, Filippo and {Di Cosimo}, Serena",

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AU - Gevorgyan, Arpine

AU - Bregni, Giacomo

AU - Galli, Giulia

AU - Zanardi, Elisa

AU - De Braud, Filippo

AU - Di Cosimo, Serena

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.

AB - Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.

KW - Breast carcinoma

KW - Neuroendocrine carcinoma

KW - Trastuzumab

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DO - 10.1159/000453572

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JF - Breast Care

SN - 1661-3791

IS - 6

ER -

HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature

Abstract

Keywords

ASJC Scopus subject areas

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