HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature

Arpine Gevorgyan, Giacomo Bregni, Giulia Galli, Elisa Zanardi, Filippo De Braud, Serena Di Cosimo

Research output: Contribution to journalReview articlepeer-review


Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.

Original languageEnglish
Pages (from-to)424-426
Number of pages3
JournalBreast Care
Issue number6
Publication statusPublished - Dec 1 2016


  • Breast carcinoma
  • Neuroendocrine carcinoma
  • Trastuzumab

ASJC Scopus subject areas

  • Surgery
  • Oncology


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