Abstract
Several studies of DNA vaccination against HER2/neu showed the effectiveness of immunization protocols in models of transplantable or spontaneous tumors. The DNA delivery system plays a crucial role in the success of DNA vaccination. In particular, our studies of DNA vaccination against HER2/neu tumor antigen showed that intramuscular injection of the vaccine followed by electroporation elicits an optimal protection against the development of spontaneous HER2/neu- tumors occurring in transgenic mice.
| Original language | English |
|---|---|
| Pages (from-to) | 473-485 |
| Number of pages | 13 |
| Journal | Methods in molecular biology (Clifton, N.J.) |
| Volume | 423 |
| Publication status | Published - 2008 |
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ASJC Scopus subject areas
- Molecular Biology
- Genetics
Cite this
HER2/neu DNA vaccination for breast tumors. / Smorlesi, Arianna; Papalini, Francesca; Pierpaoli, Sara; Provinciali, Mauro.
In: Methods in molecular biology (Clifton, N.J.), Vol. 423, 2008, p. 473-485.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - HER2/neu DNA vaccination for breast tumors.
AU - Smorlesi, Arianna
AU - Papalini, Francesca
AU - Pierpaoli, Sara
AU - Provinciali, Mauro
PY - 2008
Y1 - 2008
N2 - Several studies of DNA vaccination against HER2/neu showed the effectiveness of immunization protocols in models of transplantable or spontaneous tumors. The DNA delivery system plays a crucial role in the success of DNA vaccination. In particular, our studies of DNA vaccination against HER2/neu tumor antigen showed that intramuscular injection of the vaccine followed by electroporation elicits an optimal protection against the development of spontaneous HER2/neu- tumors occurring in transgenic mice.
AB - Several studies of DNA vaccination against HER2/neu showed the effectiveness of immunization protocols in models of transplantable or spontaneous tumors. The DNA delivery system plays a crucial role in the success of DNA vaccination. In particular, our studies of DNA vaccination against HER2/neu tumor antigen showed that intramuscular injection of the vaccine followed by electroporation elicits an optimal protection against the development of spontaneous HER2/neu- tumors occurring in transgenic mice.
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UR - http://www.scopus.com/inward/citedby.url?scp=44649178633&partnerID=8YFLogxK
M3 - Article
C2 - 18370223
AN - SCOPUS:44649178633
VL - 423
SP - 473
EP - 485
JO - Methods in Molecular Biology
JF - Methods in Molecular Biology
SN - 1064-3745
ER -