Hereditary motor and sensory neuropathies: A genetic and epidemiological study in the province of Turin, Italy

A. Chiò; A. Tribolo; F. Brignolio; M. Leone; P. Meineri; M. G. Rosso; M. Mostert; D. Schiffer

doi:10.1007/BF02335741

Hereditary motor and sensory neuropathies: A genetic and epidemiological study in the province of Turin, Italy

A. Chiò, A. Tribolo, F. Brignolio, M. Leone, P. Meineri, M. G. Rosso, M. Mostert, D. Schiffer

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article

Abstract

A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.

Original language	English
Pages (from-to)	369-374
Number of pages	6
Journal	Italian Journal of Neurological Sciences
Volume	8
Issue number	4
DOIs	https://doi.org/10.1007/BF02335741
Publication status	Published - Aug 1987

Keywords

genetic epidemiology
Hereditary motor and sensory neuropathies
survival

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

Access to Document

10.1007/BF02335741

Fingerprint Dive into the research topics of 'Hereditary motor and sensory neuropathies: A genetic and epidemiological study in the province of Turin, Italy'. Together they form a unique fingerprint.

Cite this

Chiò, A., Tribolo, A., Brignolio, F., Leone, M., Meineri, P., Rosso, M. G., Mostert, M., & Schiffer, D. (1987). Hereditary motor and sensory neuropathies: A genetic and epidemiological study in the province of Turin, Italy. Italian Journal of Neurological Sciences, 8(4), 369-374. https://doi.org/10.1007/BF02335741

@article{f9da6711fef447c18cdc04343d775388,

title = "Hereditary motor and sensory neuropathies: A genetic and epidemiological study in the province of Turin, Italy",

abstract = "A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.",

keywords = "genetic epidemiology, Hereditary motor and sensory neuropathies, survival",

author = "A. Chi{\`o} and A. Tribolo and F. Brignolio and M. Leone and P. Meineri and Rosso, {M. G.} and M. Mostert and D. Schiffer",

year = "1987",

month = aug,

doi = "10.1007/BF02335741",

language = "English",

volume = "8",

pages = "369--374",

journal = "Italian Journal of Neurological Sciences",

issn = "0392-0461",

publisher = "Springer Verlag",

number = "4",

}

TY - JOUR

T1 - Hereditary motor and sensory neuropathies

T2 - A genetic and epidemiological study in the province of Turin, Italy

AU - Chiò, A.

AU - Tribolo, A.

AU - Brignolio, F.

AU - Leone, M.

AU - Meineri, P.

AU - Rosso, M. G.

AU - Mostert, M.

AU - Schiffer, D.

PY - 1987/8

Y1 - 1987/8

N2 - A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.

AB - A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.

KW - genetic epidemiology

KW - Hereditary motor and sensory neuropathies

KW - survival

UR - http://www.scopus.com/inward/record.url?scp=0023390964&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023390964&partnerID=8YFLogxK

U2 - 10.1007/BF02335741

DO - 10.1007/BF02335741

M3 - Article

C2 - 3500148

AN - SCOPUS:0023390964

VL - 8

SP - 369

EP - 374

JO - Italian Journal of Neurological Sciences

JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 4

ER -