Abstract
A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.
| Original language | English |
|---|---|
| Pages (from-to) | 369-374 |
| Number of pages | 6 |
| Journal | Italian Journal of Neurological Sciences |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 1987 |
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Keywords
- genetic epidemiology
- Hereditary motor and sensory neuropathies
- survival
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Hereditary motor and sensory neuropathies : A genetic and epidemiological study in the province of Turin, Italy. / Chiò, A.; Tribolo, A.; Brignolio, F.; Leone, M.; Meineri, P.; Rosso, M. G.; Mostert, M.; Schiffer, D.
In: Italian Journal of Neurological Sciences, Vol. 8, No. 4, 08.1987, p. 369-374.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hereditary motor and sensory neuropathies
T2 - A genetic and epidemiological study in the province of Turin, Italy
AU - Chiò, A.
AU - Tribolo, A.
AU - Brignolio, F.
AU - Leone, M.
AU - Meineri, P.
AU - Rosso, M. G.
AU - Mostert, M.
AU - Schiffer, D.
PY - 1987/8
Y1 - 1987/8
N2 - A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.
AB - A clinical, genetic and epidemiological study of hereditary motor and sensory neuropathies (HMSN) was performed in the province of Turin, Italy. The patients were allocated to 5 groups, according to genetic and electroneurographic features. The high proportion of males among recessive and sporadic cases in the present series may suggest the existence of a recessive X-linked form of the disease. The crude prevalence rate was 3.18 (± 0.72)/100.000 population for all cases. The slow progression rate and the frequently mild symptoms of the disease, already suggested in literature, are confirmed by the analysis of the survival curves of the cases.
KW - genetic epidemiology
KW - Hereditary motor and sensory neuropathies
KW - survival
UR - http://www.scopus.com/inward/record.url?scp=0023390964&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023390964&partnerID=8YFLogxK
U2 - 10.1007/BF02335741
DO - 10.1007/BF02335741
M3 - Article
C2 - 3500148
AN - SCOPUS:0023390964
VL - 8
SP - 369
EP - 374
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -