Hereditary motor and sensory neuropathy type II (HMSN-II) and neurogenic muscle hypertrophy: A case report and literature review

M. Maurelli, E. Candeloro, M. T. Egitto, E. Alfonsi

Research output: Contribution to journalArticle

Abstract

We present two siblings affected by hereditary motor and sensory type II neuropathy (HMSN-II) with neuromyotonia, and associated with muscle hypertrophy of the thighs and calves in one. We review the literature about the association between HMSN-II, neuromyotonia and muscle hypertrophy. Muscle enlargement in HMSN-II is rare and may be sporadic or under genetic control. In our patient, muscle hypertrophy was sporadic and probably due to neuromyotonia. The relationship between muscle hypertrophy and neuromyotonia can be deduced by the fact that both conditions were reduced after diphenylhydantoin treatment (200 mg/day).

Original languageEnglish
Pages (from-to)184-188
Number of pages5
JournalNeurological Sciences
Volume19
Issue number3
Publication statusPublished - 1998

Keywords

  • HMSN II
  • Muscle hypertrophy
  • Neuromyotonia

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)

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