Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: First report of a solitary lesion

Luca Morelli, Teresa Pusiol, Francesco Piscioli, Heinz Höfler, Gregor Weirich, Martin Werner, Antonello Domenico Cabras

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Kaposi's sarcoma is a neoplastic vascular lesion. Its form of onset is frequently disseminated, especially in HIV-positive patients. Its association with the infection caused by a virus of the Epstein-Barr family, human herpesvirus 8 (HHV-8), has been recently demonstrated. In this article we discuss the unusual presentation of a solitary manifestation of Kaposi's sarcoma on the penis of a 53-year-old HIV-negative patient. Polymerase chain reaction analysis of the tumor tissue was positive for HHV-8 in the tumor cells but not in the reactive stroma cells surrounding the tumor. The case is interesting for its unusual site of presentation, the young age of onset, the association with HHV-8 infection, the HIV-negative serology, and the benign course of the disease.

Original languageEnglish
Pages (from-to)28-31
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume25
Issue number1
DOIs
Publication statusPublished - Feb 2003

Fingerprint

Human Herpesvirus 8
Kaposi's Sarcoma
Herpesviridae
HIV
Herpesviridae Infections
Neoplasms
Penis
Serology
Human Herpesvirus 4
Age of Onset
Blood Vessels
Polymerase Chain Reaction
Infection

Keywords

  • Epstein-Barr virus
  • HHV-8
  • Human herpesvirus 8
  • Kaposi's sarcoma

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

Cite this

Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient : First report of a solitary lesion. / Morelli, Luca; Pusiol, Teresa; Piscioli, Francesco; Höfler, Heinz; Weirich, Gregor; Werner, Martin; Cabras, Antonello Domenico.

In: American Journal of Dermatopathology, Vol. 25, No. 1, 02.2003, p. 28-31.

Research output: Contribution to journalArticle

Morelli, Luca ; Pusiol, Teresa ; Piscioli, Francesco ; Höfler, Heinz ; Weirich, Gregor ; Werner, Martin ; Cabras, Antonello Domenico. / Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient : First report of a solitary lesion. In: American Journal of Dermatopathology. 2003 ; Vol. 25, No. 1. pp. 28-31.
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