Heterogeneity of Glut 4 content in adipose and muscle tissue of moderately obese patients with or without non-insulin dependent diabetes mellitus

L. Frittitta, B. M. Gliozzo, D. Foti, M. Astuto, F. Basile, R. Vigneri, V. Trischitta

Research output: Contribution to journalArticle

Abstract

We quantified Glut 4 glucose transporter content, by immunoblot technique, in adipose and muscle tissue of 6 lean controls (BMI=22±0.6, mean±SE) and 15 moderately obese patients either without (n=9, BMI=29±0.6) or with NIDDM (n=6, BMI=30±1.9). In adipose tissue, the average Glut 4 content, expressed as arbitrary densitometric units, was significantly (p

Original languageEnglish
Pages (from-to)17-20
Number of pages4
JournalDiabetes, Nutrition and Metabolism - Clinical and Experimental
Volume7
Issue number1
Publication statusPublished - 1994

Keywords

  • Glut 4
  • Human tissues
  • Insulin resistance
  • NIDDM
  • Obesity

ASJC Scopus subject areas

  • Food Science
  • Endocrinology
  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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