Two case reports are presented (LR, 49 years old woman, and PA, 62 year old man) who in 1995 came to our observation for a 2-yearperiod of word-finding difficulties. In both patients case history was unremarkable, while on longitudinal evaluation a progressive impairment of the lexical-semantic aspects of language was found. However, LR's deficits In naming and word comprehension appear to be the result of a profound breakdown of semantic knowledge, whercas in PA we between semantic and phonological output system. General intelligence, non-lexical aspects of language and visual perception were spared. Both patients are still autonomous in every day-life. Different evolution of progressive fluent aphasia, MRI sites of focal cortical atrophy, PET data anti implications to the cognitive model of semantic memory are discussed.
|Number of pages||1|
|Journal||Italian Journal of Neurological Sciences|
|Publication status||Published - 1997|
ASJC Scopus subject areas
- Clinical Neurology