Heterogeneity of root and nerve ultrasound pattern in CIDP patients

L. Padua, G. Granata, M. Sabatelli, M. Inghilleri, M. Lucchetta, M. Luigetti, D. Coraci, C. Martinoli, C. Briani

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Objective: The few published ultrasound (US) studies on chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) report diffusely increased cross-sectional area (CSA) of nerves. The data are, however, heterogeneous and correlations with clinical history or disease severity are lacking. Methods: Thirty-four patients with CIDP underwent US nerve evaluation by two neurologists blinded to clinical data. US nerve pattern for each patient was defined by a third neurologist blinded to clinical data. Three US classes were identified based on CSA and echogenicity: large nerves with hypoechoic nerves/fascicles (class 1); large nerves with heterogeneous hypo- and hyperechoic fascicles (class 2); normal size nerve but abnormal hyperechoic array (class 3). Results: In all patients, US nerve changes were observed: in most of the cases, enlarged nerves or nerve segments were observed. The three 'classes' of US nerve changes significantly correlated (R: 0.68, p

Original languageEnglish
Pages (from-to)160-165
Number of pages6
JournalClinical Neurophysiology
Volume125
Issue number1
DOIs
Publication statusPublished - Jan 2014

Fingerprint

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Neurologists

Keywords

  • Autoimmune diseases
  • Chronic inflammatory demyelinating polyneuropathy
  • Peripheral neuropathy
  • Ultrasound

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)
  • Sensory Systems

Cite this

Padua, L., Granata, G., Sabatelli, M., Inghilleri, M., Lucchetta, M., Luigetti, M., ... Briani, C. (2014). Heterogeneity of root and nerve ultrasound pattern in CIDP patients. Clinical Neurophysiology, 125(1), 160-165. https://doi.org/10.1016/j.clinph.2013.07.023

Heterogeneity of root and nerve ultrasound pattern in CIDP patients. / Padua, L.; Granata, G.; Sabatelli, M.; Inghilleri, M.; Lucchetta, M.; Luigetti, M.; Coraci, D.; Martinoli, C.; Briani, C.

In: Clinical Neurophysiology, Vol. 125, No. 1, 01.2014, p. 160-165.

Research output: Contribution to journalArticle

Padua, L, Granata, G, Sabatelli, M, Inghilleri, M, Lucchetta, M, Luigetti, M, Coraci, D, Martinoli, C & Briani, C 2014, 'Heterogeneity of root and nerve ultrasound pattern in CIDP patients', Clinical Neurophysiology, vol. 125, no. 1, pp. 160-165. https://doi.org/10.1016/j.clinph.2013.07.023
Padua, L. ; Granata, G. ; Sabatelli, M. ; Inghilleri, M. ; Lucchetta, M. ; Luigetti, M. ; Coraci, D. ; Martinoli, C. ; Briani, C. / Heterogeneity of root and nerve ultrasound pattern in CIDP patients. In: Clinical Neurophysiology. 2014 ; Vol. 125, No. 1. pp. 160-165.
@article{a4ea07af0de14f4abe505987cb80dd95,
title = "Heterogeneity of root and nerve ultrasound pattern in CIDP patients",
abstract = "Objective: The few published ultrasound (US) studies on chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) report diffusely increased cross-sectional area (CSA) of nerves. The data are, however, heterogeneous and correlations with clinical history or disease severity are lacking. Methods: Thirty-four patients with CIDP underwent US nerve evaluation by two neurologists blinded to clinical data. US nerve pattern for each patient was defined by a third neurologist blinded to clinical data. Three US classes were identified based on CSA and echogenicity: large nerves with hypoechoic nerves/fascicles (class 1); large nerves with heterogeneous hypo- and hyperechoic fascicles (class 2); normal size nerve but abnormal hyperechoic array (class 3). Results: In all patients, US nerve changes were observed: in most of the cases, enlarged nerves or nerve segments were observed. The three 'classes' of US nerve changes significantly correlated (R: 0.68, p",
keywords = "Autoimmune diseases, Chronic inflammatory demyelinating polyneuropathy, Peripheral neuropathy, Ultrasound",
author = "L. Padua and G. Granata and M. Sabatelli and M. Inghilleri and M. Lucchetta and M. Luigetti and D. Coraci and C. Martinoli and C. Briani",
year = "2014",
month = "1",
doi = "10.1016/j.clinph.2013.07.023",
language = "English",
volume = "125",
pages = "160--165",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Heterogeneity of root and nerve ultrasound pattern in CIDP patients

AU - Padua, L.

AU - Granata, G.

AU - Sabatelli, M.

AU - Inghilleri, M.

AU - Lucchetta, M.

AU - Luigetti, M.

AU - Coraci, D.

AU - Martinoli, C.

AU - Briani, C.

PY - 2014/1

Y1 - 2014/1

N2 - Objective: The few published ultrasound (US) studies on chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) report diffusely increased cross-sectional area (CSA) of nerves. The data are, however, heterogeneous and correlations with clinical history or disease severity are lacking. Methods: Thirty-four patients with CIDP underwent US nerve evaluation by two neurologists blinded to clinical data. US nerve pattern for each patient was defined by a third neurologist blinded to clinical data. Three US classes were identified based on CSA and echogenicity: large nerves with hypoechoic nerves/fascicles (class 1); large nerves with heterogeneous hypo- and hyperechoic fascicles (class 2); normal size nerve but abnormal hyperechoic array (class 3). Results: In all patients, US nerve changes were observed: in most of the cases, enlarged nerves or nerve segments were observed. The three 'classes' of US nerve changes significantly correlated (R: 0.68, p

AB - Objective: The few published ultrasound (US) studies on chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) report diffusely increased cross-sectional area (CSA) of nerves. The data are, however, heterogeneous and correlations with clinical history or disease severity are lacking. Methods: Thirty-four patients with CIDP underwent US nerve evaluation by two neurologists blinded to clinical data. US nerve pattern for each patient was defined by a third neurologist blinded to clinical data. Three US classes were identified based on CSA and echogenicity: large nerves with hypoechoic nerves/fascicles (class 1); large nerves with heterogeneous hypo- and hyperechoic fascicles (class 2); normal size nerve but abnormal hyperechoic array (class 3). Results: In all patients, US nerve changes were observed: in most of the cases, enlarged nerves or nerve segments were observed. The three 'classes' of US nerve changes significantly correlated (R: 0.68, p

KW - Autoimmune diseases

KW - Chronic inflammatory demyelinating polyneuropathy

KW - Peripheral neuropathy

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=84890206906&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890206906&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2013.07.023

DO - 10.1016/j.clinph.2013.07.023

M3 - Article

C2 - 24099922

AN - SCOPUS:84890206906

VL - 125

SP - 160

EP - 165

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 1

ER -