Heterotopic gastric mucosa of the tongue and the oesophagus

M. Melato, A. Ferlito

Research output: Contribution to journalArticlepeer-review


A case of gastric heterotopia of the tongue and one of heterotopic gastric mucosa of the esophagus are described. From a review of the world literature it appears that the present case of lingual gastric heterotopia is only the 8th so far reported and the first occurring in a woman. The site of the polypoid formation medially in the body of the tongue and its presence since birth indicate a congenital malformation. As to the observation of heterotopic gastric mucosa in the esophagus, it is worth noting that the aberrant tissue was located in a wide area between 2 sites of squamous carcinoma of the esophagus. Primary adenocarcinoma of the upper third of the esophagus is extremely rare and its histogenesis becomes even more controversial when consideration is given to some of the features of the case presented. In particular, the hypothesis that adenocarcinoma may arise from heterotopic gastric epithelium is doubtful and does not explain the origin of all adenocarcinomas in the upper third of the esophagus. The assumption that it may arise from esophageal glands and/or from tracheobranchial rests remains well founded.

Original languageEnglish
Pages (from-to)244-254
Number of pages11
Issue number4
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Otorhinolaryngology


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