Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers

M. D'Incalci; P. Farina; C. Sessa; C. Mangioni; S. Garattini

Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers

M. D'Incalci, P. Farina, C. Sessa, C. Mangioni, S. Garattini

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

The distribution of hexamethylmelamine (HMM) was investigated in surgical biopsies from 12 patients with pelvic cancer who were given an oral dose of 200 mg at 2-24 hours before the operation. The highest concentrations of HMM were found in tissues, such as omentum and subcutaneous tissue, that have a predominant lipidic component. HMM concentrations in the primary tumor were lower than in other tissues and were similar to those in plasma. HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter

Original language	English
Pages (from-to)	231-235
Number of pages	5
Journal	Cancer Treatment Reports
Volume	66
Issue number	2
Publication status	Published - 1982

ASJC Scopus subject areas

Cancer Research
Oncology

Fingerprint Dive into the research topics of 'Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers'. Together they form a unique fingerprint.

Cite this

@article{127804afebdf468798488e107de114a5,

title = "Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers",

abstract = "The distribution of hexamethylmelamine (HMM) was investigated in surgical biopsies from 12 patients with pelvic cancer who were given an oral dose of 200 mg at 2-24 hours before the operation. The highest concentrations of HMM were found in tissues, such as omentum and subcutaneous tissue, that have a predominant lipidic component. HMM concentrations in the primary tumor were lower than in other tissues and were similar to those in plasma. HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter ",

author = "M. D'Incalci and P. Farina and C. Sessa and C. Mangioni and S. Garattini",

year = "1982",

language = "English",

volume = "66",

pages = "231--235",

journal = "Cancer Treatment Reports",

issn = "0361-5960",

publisher = "U.S. National Cancer Institute",

number = "2",

}

TY - JOUR

T1 - Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers

AU - D'Incalci, M.

AU - Farina, P.

AU - Sessa, C.

AU - Mangioni, C.

AU - Garattini, S.

PY - 1982

Y1 - 1982

N2 - The distribution of hexamethylmelamine (HMM) was investigated in surgical biopsies from 12 patients with pelvic cancer who were given an oral dose of 200 mg at 2-24 hours before the operation. The highest concentrations of HMM were found in tissues, such as omentum and subcutaneous tissue, that have a predominant lipidic component. HMM concentrations in the primary tumor were lower than in other tissues and were similar to those in plasma. HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter

AB - The distribution of hexamethylmelamine (HMM) was investigated in surgical biopsies from 12 patients with pelvic cancer who were given an oral dose of 200 mg at 2-24 hours before the operation. The highest concentrations of HMM were found in tissues, such as omentum and subcutaneous tissue, that have a predominant lipidic component. HMM concentrations in the primary tumor were lower than in other tissues and were similar to those in plasma. HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter

UR - http://www.scopus.com/inward/record.url?scp=0020084873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020084873&partnerID=8YFLogxK

M3 - Article

C2 - 6799199

AN - SCOPUS:0020084873

VL - 66

SP - 231

EP - 235

JO - Cancer Treatment Reports

JF - Cancer Treatment Reports

SN - 0361-5960

IS - 2

ER -