HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT: Report of a pediatric case and literature review

Ilaria Sala; Maura Faraci; Gian M. Magnano; Angela Sementa; Eddi Di Marco; Alberto Garaventa; Concetta Micalizzi; Edoardo Lanino; Giuseppe Morreale; Cristina Moroni; Elio Castagnola

doi:10.1111/j.1399-3046.2010.01315.x

HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT: Report of a pediatric case and literature review

Ilaria Sala, Maura Faraci, Gian M. Magnano, Angela Sementa, Eddi Di Marco, Alberto Garaventa, Concetta Micalizzi, Edoardo Lanino, Giuseppe Morreale, Cristina Moroni, Elio Castagnola

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.

Original language	English
Journal	Pediatric Transplantation
Volume	15
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-3046.2010.01315.x
Publication status	Published - Feb 2011

Keywords

allogeneic HSCT
children
Kaposi sarcoma

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Transplantation

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10.1111/j.1399-3046.2010.01315.x

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In: Pediatric Transplantation, Vol. 15, No. 1, 02.2011.

Research output: Contribution to journal › Article › peer-review

Sala, Ilaria ; Faraci, Maura ; Magnano, Gian M. ; Sementa, Angela ; Di Marco, Eddi ; Garaventa, Alberto ; Micalizzi, Concetta ; Lanino, Edoardo ; Morreale, Giuseppe ; Moroni, Cristina ; Castagnola, Elio. / HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT : Report of a pediatric case and literature review. In: Pediatric Transplantation. 2011 ; Vol. 15, No. 1.

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abstract = "An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.",

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AU - Sementa, Angela

AU - Di Marco, Eddi

AU - Garaventa, Alberto

AU - Micalizzi, Concetta

AU - Lanino, Edoardo

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AU - Moroni, Cristina

AU - Castagnola, Elio

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AB - An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.

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HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT: Report of a pediatric case and literature review

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Keywords

ASJC Scopus subject areas

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