TY - JOUR
T1 - HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT
T2 - Report of a pediatric case and literature review
AU - Sala, Ilaria
AU - Faraci, Maura
AU - Magnano, Gian M.
AU - Sementa, Angela
AU - Di Marco, Eddi
AU - Garaventa, Alberto
AU - Micalizzi, Concetta
AU - Lanino, Edoardo
AU - Morreale, Giuseppe
AU - Moroni, Cristina
AU - Castagnola, Elio
PY - 2011/2
Y1 - 2011/2
N2 - An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.
AB - An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.
KW - allogeneic HSCT
KW - children
KW - Kaposi sarcoma
UR - http://www.scopus.com/inward/record.url?scp=78751667373&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78751667373&partnerID=8YFLogxK
U2 - 10.1111/j.1399-3046.2010.01315.x
DO - 10.1111/j.1399-3046.2010.01315.x
M3 - Article
C2 - 20345616
AN - SCOPUS:78751667373
VL - 15
JO - Pediatric Transplantation
JF - Pediatric Transplantation
SN - 1397-3142
IS - 1
ER -