High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis: In-stent restenosis assessment by low-dose MDCT

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Abstract

Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈

Original languageEnglish
Pages (from-to)1430-1438
Number of pages9
JournalEuropean Radiology
Volume21
Issue number7
DOIs
Publication statusPublished - Jul 2011

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Coronary Angiography
Stents
Electrocardiography
Tomography
Artifacts
Computed Tomography Angiography
Angiography
Catheters
Radiation

Keywords

  • Computed tomography
  • Coronary arteries
  • Coronary stents
  • In-stent restenosis
  • Invasive coronary angiography
  • Radiation dose

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

@article{d64762afa6c1432d916ba96f1e84593e,
title = "High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis: In-stent restenosis assessment by low-dose MDCT",
abstract = "Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24{\%} in both groups. The overall evaluability was similar (93{\%} in group 1 vs 95{\%} in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100{\%}, 100{\%} and 99{\%}, respectively) than in group 2 (97{\%}, 91{\%} and 95{\%}, respectively, p∈",
keywords = "Computed tomography, Coronary arteries, Coronary stents, In-stent restenosis, Invasive coronary angiography, Radiation dose",
author = "Daniele Andreini and Gianluca Pontone and Bartorelli, {Antonio L.} and Saima Mushtaq and Daniela Trabattoni and Erika Bertella and Sarah Cortinovis and Andrea Annoni and Alberto Formenti and Giovanni Ballerini and Piergiuseppe Agostoni and Cesare Fiorentini and Mauro Pepi",
year = "2011",
month = "7",
doi = "10.1007/s00330-011-2085-7",
language = "English",
volume = "21",
pages = "1430--1438",
journal = "European Radiology",
issn = "0938-7994",
publisher = "Springer Verlag",
number = "7",

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TY - JOUR

T1 - High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis

T2 - In-stent restenosis assessment by low-dose MDCT

AU - Andreini, Daniele

AU - Pontone, Gianluca

AU - Bartorelli, Antonio L.

AU - Mushtaq, Saima

AU - Trabattoni, Daniela

AU - Bertella, Erika

AU - Cortinovis, Sarah

AU - Annoni, Andrea

AU - Formenti, Alberto

AU - Ballerini, Giovanni

AU - Agostoni, Piergiuseppe

AU - Fiorentini, Cesare

AU - Pepi, Mauro

PY - 2011/7

Y1 - 2011/7

N2 - Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈

AB - Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈

KW - Computed tomography

KW - Coronary arteries

KW - Coronary stents

KW - In-stent restenosis

KW - Invasive coronary angiography

KW - Radiation dose

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