High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis: In-stent restenosis assessment by low-dose MDCT

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Abstract

Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈

Original languageEnglish
Pages (from-to)1430-1438
Number of pages9
JournalEuropean Radiology
Volume21
Issue number7
DOIs
Publication statusPublished - Jul 2011

Keywords

  • Computed tomography
  • Coronary arteries
  • Coronary stents
  • In-stent restenosis
  • Invasive coronary angiography
  • Radiation dose

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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