High-dose radiation-induced meningioma in children: Case report and critical review of the literature

E. Caroli, M. Salvati, R. Roperto, G. D'Andrea, L. Ferrante

Research output: Contribution to journalArticlepeer-review

Abstract

Object: High-dose radiation-induced meningiomas in children are a rare occurrence. We discuss the clinical data and the differences of these rare tumors from those of spontaneous counterpart and radiation-induced meningiomas of the adult population. Case Report: We report a case of meningothelial meningioma, which occurred in a 9-year-old boy who underwent radiotherapy for a parieto-occipital cutaneous angioma. In addition, we collected 18 cases of high-dose radiation-induced meningiomas in children from a literature review with Medline. Results: Radiation-induced meningiomas in children show a female predominance, a short latency period that seems to be related to the age at irradiation, and an aggressive behaviour. Conclusion: Exposure to the potentially carcinogenic effects of radiotherapy should be reserved only for tumors that demonstrate subsequent progression. A meticulous follow-up of patients treated with radiation therapy is mandatory.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalZentralblatt fur Neurochirurgie
Volume66
Issue number1
DOIs
Publication statusPublished - 2005

Keywords

  • Children
  • Meningioma
  • Radiation-induced tumors
  • Radiotherapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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