Abstract
The authors review three personal cases of patients who developed cerebral meningiomas following high-dose radiotherapy for acute lymphoblastic leukemia. Two patients were female and one male. Their ages when the leukemia appeared were between 11 and 15 years. All patients were treated with a course of prophylactic irradiation to the neuraxis for a total dose of 24 Gy. After an average interval of 10.4 years, all three patients presented a meningioma; histologically, one was meningothelial and two were fibrous. All three meningiomas presented atypical features. At follow-up 1, 4, and 4 years respectively after surgery, none of these patients presents neurological deficits or neuroradiological signs of recurrence. Forty-nine cases of high-dose radiation-induced meningioma are also reviewed.
| Original language | English |
|---|---|
| Pages (from-to) | 266-269 |
| Number of pages | 4 |
| Journal | Child's Nervous System |
| Volume | 12 |
| Issue number | 5 |
| Publication status | Published - May 1996 |
Keywords
- Meningioma
- Radiotherapy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology