Abstract
The authors review three personal cases of patients who developed cerebral meningiomas following high-dose radiotherapy for acute lymphoblastic leukemia. Two patients were female and one male. Their ages when the leukemia appeared were between 11 and 15 years. All patients were treated with a course of prophylactic irradiation to the neuraxis for a total dose of 24 Gy. After an average interval of 10.4 years, all three patients presented a meningioma; histologically, one was meningothelial and two were fibrous. All three meningiomas presented atypical features. At follow-up 1, 4, and 4 years respectively after surgery, none of these patients presents neurological deficits or neuroradiological signs of recurrence. Forty-nine cases of high-dose radiation-induced meningioma are also reviewed.
| Original language | English |
|---|---|
| Pages (from-to) | 266-269 |
| Number of pages | 4 |
| Journal | Child's Nervous System |
| Volume | 12 |
| Issue number | 5 |
| Publication status | Published - May 1996 |
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Keywords
- Meningioma
- Radiotherapy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
High-dose radiation-induced meningiomas following acute lymphoblastic leukemia in children. / Salvati, Maurizio; Cervoni, Luigi; Artico, Marco.
In: Child's Nervous System, Vol. 12, No. 5, 05.1996, p. 266-269.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High-dose radiation-induced meningiomas following acute lymphoblastic leukemia in children
AU - Salvati, Maurizio
AU - Cervoni, Luigi
AU - Artico, Marco
PY - 1996/5
Y1 - 1996/5
N2 - The authors review three personal cases of patients who developed cerebral meningiomas following high-dose radiotherapy for acute lymphoblastic leukemia. Two patients were female and one male. Their ages when the leukemia appeared were between 11 and 15 years. All patients were treated with a course of prophylactic irradiation to the neuraxis for a total dose of 24 Gy. After an average interval of 10.4 years, all three patients presented a meningioma; histologically, one was meningothelial and two were fibrous. All three meningiomas presented atypical features. At follow-up 1, 4, and 4 years respectively after surgery, none of these patients presents neurological deficits or neuroradiological signs of recurrence. Forty-nine cases of high-dose radiation-induced meningioma are also reviewed.
AB - The authors review three personal cases of patients who developed cerebral meningiomas following high-dose radiotherapy for acute lymphoblastic leukemia. Two patients were female and one male. Their ages when the leukemia appeared were between 11 and 15 years. All patients were treated with a course of prophylactic irradiation to the neuraxis for a total dose of 24 Gy. After an average interval of 10.4 years, all three patients presented a meningioma; histologically, one was meningothelial and two were fibrous. All three meningiomas presented atypical features. At follow-up 1, 4, and 4 years respectively after surgery, none of these patients presents neurological deficits or neuroradiological signs of recurrence. Forty-nine cases of high-dose radiation-induced meningioma are also reviewed.
KW - Meningioma
KW - Radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=0030009026&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030009026&partnerID=8YFLogxK
M3 - Article
VL - 12
SP - 266
EP - 269
JO - Child's Nervous System
JF - Child's Nervous System
SN - 0256-7040
IS - 5
ER -