High-grade mucoepidermoid carcinoma of the breast. Fine needle aspiration cytology and clinicopathologic study of a case

G. Pettinato, L. Insabato, A. De Chiara, A. Manco, G. Petrella

Research output: Contribution to journalArticle

Abstract

A primary high-grade mucoepidermoid carcinoma of the breast was evaluated preoperatively by fine needle aspiration (FNA) cytology in a 72-year-old woman. The smears showed a mixed pattern consisting of clusters of poorly differentiated squamous cells, keratinized squamous cells and vacuolated mucin-secreting cells. The subsequent mastectomy specimen showed a tumor with the features of a high-grade mucoepidermoid carcinoma. Electron microscopy confirmed the diagnosis, reflecting the epidermoid and glandular differentiation of the tumor. The course was rapidly fatal, and the patient died a few months after presentation. A review of the literature indicated that mucoepidermoid carcinoma of the breast is a very rare neoplasm; and FNA cytologic features described in this report may constitute a basis to preoperatively recognize this tumor.

Original languageEnglish
Pages (from-to)195-200
Number of pages6
JournalActa Cytologica
Volume33
Issue number2
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Cell Biology
  • Anatomy
  • Histology

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