High-grade serous tumor arising from fallopian tube in a BRCA mutation carrier after prophylactic oophorectomy

Domenica Lorusso; Roberta Di Rocco; Maria Mancini; Francesco Raspagliesi

doi:10.1159/000346339

High-grade serous tumor arising from fallopian tube in a BRCA mutation carrier after prophylactic oophorectomy

Domenica Lorusso, Roberta Di Rocco, Maria Mancini, Francesco Raspagliesi

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

We present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube which previously had not been removed during prophylactic surgery. This case report suggests that much effort should be made during prophylactic oophorectomy to completely remove the tubes, especially in light of the recent pathologic theories on the tubal origin of ovarian cancer.

Original language	English
Pages (from-to)	21-24
Number of pages	4
Journal	Case Reports in Oncology
Volume	6
Issue number	1
DOIs	https://doi.org/10.1159/000346339
Publication status	Published - Jan 2013

Keywords

BRCA mutation
Fallopian tube
Kurman's hypothesis
Ovarian cancer

ASJC Scopus subject areas

Oncology

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KW - Kurman's hypothesis

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High-grade serous tumor arising from fallopian tube in a BRCA mutation carrier after prophylactic oophorectomy

Abstract

Keywords

ASJC Scopus subject areas

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