High-grade serous tumor arising from fallopian tube in a BRCA mutation carrier after prophylactic oophorectomy

Domenica Lorusso, Roberta Di Rocco, Maria Mancini, Francesco Raspagliesi

Research output: Contribution to journalArticle


We present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube which previously had not been removed during prophylactic surgery. This case report suggests that much effort should be made during prophylactic oophorectomy to completely remove the tubes, especially in light of the recent pathologic theories on the tubal origin of ovarian cancer.

Original languageEnglish
Pages (from-to)21-24
Number of pages4
JournalCase Reports in Oncology
Issue number1
Publication statusPublished - Jan 2013



  • BRCA mutation
  • Fallopian tube
  • Kurman's hypothesis
  • Ovarian cancer

ASJC Scopus subject areas

  • Oncology

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