High incidence of gastrointestinal cancer in a family with ataxia-telangiectasia.

M. Ceroni, J. Karau, P. Pergami, D. Ferrandi, F. Savoldi

Research output: Contribution to journalArticlepeer-review

Abstract

Literature suggests that not only homozygotes but also heterozygotes for ataxia-telangiectasia have a high incidence of cancer, probably due to an impairment in DNA repair. The most frequent associations are with breast, lung, bladder, prostate and stomach tumors, while no correlation with colorectal cancer has been demonstrated. The affected family reported in this paper seems to have a high incidence of gastrointestinal tract tumors, including the colorectal ones.

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalActa Neurologica
Volume16
Issue number1-2
Publication statusPublished - Feb 1994

ASJC Scopus subject areas

  • Clinical Neurology

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